Acute generalized exanthematous pustulosis associated with coccidiomycosis infection

McBride, M; Davis, Mitchell S.; Casey, Michael A.; Lam, Travis

doi:10.1016/j.jdcr.2020.12.026

Cited by 3 publications

(3 citation statements)

References 9 publications

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“… 8 For example, in a case of AGEP associated with Coccidioides infection, it was proposed that both Coccidioides infection and AGEP showed similar changes in cytokines dominated by Th1 inflammation. 18 S. pettenkoferi is a relatively rare CoNS, the clinical significance and epidemiology of S. pettenkoferi are still not sufficient. Studies of other CoNS showed that they can induce the expression of IL-6, IL-8 and other cytokines in animals.…”

Section: Discussionmentioning

confidence: 99%

“…In some cases of infection-associated AGEP with clear laboratory evidence, aggressive anti-infective therapy is considered necessary. 18 Over the past few years, it was highlighted the prominent role of IL-17 in the pathogenesis of AGEP. 17 , 23 Secukinumab has promising outcome for the AGEP patients resistant to hormone therapy.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Case Report of Possibly Related Acute Generalized Exanthematous Pustulosis with Staphylococcus pettenkoferi

Wang¹,

Bai²,

Qiao³

2023

CCID

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Case Report of Possibly Related Acute Generalized Exanthematous Pustulosis with Staphylococcus pettenkoferi

Wang¹,

Bai²,

Qiao³

2023

CCID

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Inpatient Evaluation and Management of Generalized Pustular Dermatoses

Davis,

Spencer,

Elhage

et al. 2023

Curr Derm Rep

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Purpose of Review The purpose of this paper is to discuss the evaluation and management of the most encountered pustular dermatoses in the inpatient setting. Recent Findings Generalized pustular psoriasis (GPP), acute generalized exanthematous pustulosis (AGEP), and acneiform eruptions are three pustular dermatoses encountered in the inpatient setting. New insights into the pathophysiology of these diseases are guiding the investigation of novel treatments for pustular dermatoses. Summary Although cases of pustular dermatoses are often benign and self-limited, careful evaluation and management are indicated as severe cases may pose legitimate health risks and require systemic therapy. Biologic agents are playing a larger role in the management of pustular dermatoses such as GPP.

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Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management

et al. 2023

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Acute generalized exanthematous pustulosis (AGEP) is a rare, acute, severe cutaneous adverse reaction mainly attributed to drugs, although other triggers, including infections, vaccinations, ingestion of various substances, and spider bites, have also been described. AGEP is characterized by the development of edema and erythema followed by the eruption of multiple punctate, non-follicular, sterile pustules and subsequent desquamation. AGEP typically has a rapid onset and prompt resolution within a few weeks. The differential diagnoses for AGEP are broad and include infectious, inflammatory, and drug-induced etiologies. Diagnosis of AGEP depends on both clinical and histologic criteria, as cases of overlap with other disease processes have been reported. Management includes removal of the offending drug or treatment of the underlying cause, if necessary, and supportive care, as AGEP is a self-limited disease. This review aims to provide an overview and update on the epidemiology, pathogenesis, reported precipitating factors, differentials, diagnosis, and management of AGEP.

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Acute generalized exanthematous pustulosis associated with coccidiomycosis infection

Cited by 3 publications

References 9 publications

A Case Report of Possibly Related Acute Generalized Exanthematous Pustulosis with Staphylococcus pettenkoferi

A Case Report of Possibly Related Acute Generalized Exanthematous Pustulosis with Staphylococcus pettenkoferi

Inpatient Evaluation and Management of Generalized Pustular Dermatoses

Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management

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