Acute Haematogenous Osteitis in Childhood

White, Matthew; Dennison, Wallace M.

doi:10.1302/0301-620x.34b4.608

Cited by 36 publications

(12 citation statements)

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“…In general our results compare favourably with those of others who have been treating acute osteomyelitis by medullary decompression (White and Dennison, 1952;Trueta and Morgan, 1954).…”

Section: Resultssupporting

confidence: 83%

“…Our cases have recently been reviewed by one of us (Shandling, 1960), and our findings in regard to age and sex incidence, social status, pre-existing septic foci and predisposing trauma are in keeping with those of others (Altemeier and Helmsworth, 1945;Agerholm and Trueta, 1946;Caldwell and Wickstrom, 1950;White and Dennison, 1952;Dennison, 1952;Trueta and Morgan, 1954). The bones most commonly affected were upper tibiae, lower femora and tibiae and upper femoral shafts (Fig.…”

supporting

confidence: 72%

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Acute Haematogenous Osteomyelitis with Special Reference to Osteitis of the Neck of the Femur

Louw¹,

Shandling²

1961

Archives of Disease in Childhood

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“…In general our results compare favourably with those of others who have been treating acute osteomyelitis by medullary decompression (White and Dennison, 1952;Trueta and Morgan, 1954).…”

Section: Resultssupporting

confidence: 83%

supporting

confidence: 72%

Acute Haematogenous Osteomyelitis with Special Reference to Osteitis of the Neck of the Femur

Louw¹,

Shandling²

1961

Archives of Disease in Childhood

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“…An early study of the treatment of paediatric osteomyelitis with penicillin reported resistance rates of only 2.4%. 2 Over the next 50 years these rose rapidly to 60% to 80%, and since 1999 the rates for MRSA are addressed specifically. They vary enormously, depending largely on geographical location, from 0% in Saudi Arabia 40 to 71.4% in the USA.…”

Section: Resultsmentioning

confidence: 99%

“…1,2 Delay in diagnosis and inappropriate treatment can result in sepsis, chronic infection, disruption of longitudinal bone growth and angular deformity. 2,3 Correct and timely treatment improves outcome; however, with evolving microbiology, including the emergence of methicillin-resistant Staphylococcus aureus (MRSA), early selection of the correct antibiotic is vital.…”

mentioning

confidence: 99%

Haematogenous acute and subacute paediatric osteomyelitis

Dartnell

Ramachandran

Katchburian

2012

The Journal of Bone and Joint Surgery. British volume

311

299

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A delay in the diagnosis of paediatric acute and subacute haematogenous osteomyelitis can lead to potentially devastating morbidity. There are no definitive guidelines for diagnosis, and recommendations in the literature are generally based on expert opinions, case series and cohort studies. All articles in the English literature on paediatric osteomyelitis were searched using MEDLINE, CINAHL, EMBASE, Google Scholar, the Cochrane Library and reference lists. A total of 1854 papers were identified, 132 of which were examined in detail. All aspects of osteomyelitis were investigated in order to formulate recommendations. On admission 40% of children are afebrile. The tibia and femur are the most commonly affected long bones. Clinical examination, blood and radiological tests are only reliable for diagnosis in combination. Staphylococcus aureus is the most common organism detected, but isolation of Kingella kingae is increasing. Antibiotic treatment is usually sufficient to eradicate the infection, with a short course intravenously and early conversion to oral treatment. Surgery is indicated only in specific situations. Most studies were retrospective and there is a need for large, multicentre, randomised, controlled trials to define protocols for diagnosis and treatment. Meanwhile, evidence-based algorithms are suggested for accurate and early diagnosis and effective treatment.

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“…In addition, we assessed and compared the pathogens responsible, the routes and duration of antibiotic therapy, the need for surgery and the complications encountered with those of earlier series. [1][2][3][4][5][6][7][8][9][10] The study repeated that of Craigen, Watters and Hackett 11 on the same reference population between 1970 and 1990. By using identical methods we were able to observe trends, particularly with regard to incidence, over a period of 28 years.…”

mentioning

confidence: 75%

The changing epidemiology of acute and subacute haematogenous osteomyelitis in children

Blyth

Kincaid

Craigen

et al. 2001

The Journal of Bone and Joint Surgery. British volume

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We have reviewed the incidence of bacteriologically or radiologically confirmed acute haematogenous osteomyelitis in children under 13 years of age resident in the area of the Greater Glasgow Health Board between 1990 and 1997. In this period there was a fall of 44% in the incidence of both acute and subacute osteomyelitis, mainly involving the acute form (p = 0.005). This mirrors the decline of just over 50% previously reported in the same population between 1970 and 1990. Using multiple regression analysis a decline in incidence of 0.185 cases per 100 000 population per year was calculated for the 28-year period (p < 0.001).Staphylococcus was the most commonly isolated pathogen (70%). Only 20% of patients required surgery and there was a low rate of complications (10%). In general, patients with a subacute presentation followed a benign course and there were no complications or long-term sequelae in this group.Haematogenous osteomyelitis in children in this area is becoming a rare disease with an annual incidence of 2.9 new cases per 100 000 population per year. Our aim was to assess the changing epidemiology of acute and subacute osteomyelitis in a single health district from 1990 to 1997, with particular reference to the incidence and the type (acute or subacute) and site of presentation. In addition, we assessed and compared the pathogens responsible, the routes and duration of antibiotic therapy, the need for surgery and the complications encountered with those of earlier series.

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Acute Haematogenous Osteitis in Childhood

Cited by 36 publications

References 0 publications

Acute Haematogenous Osteomyelitis with Special Reference to Osteitis of the Neck of the Femur

Acute Haematogenous Osteomyelitis with Special Reference to Osteitis of the Neck of the Femur

Haematogenous acute and subacute paediatric osteomyelitis

The changing epidemiology of acute and subacute haematogenous osteomyelitis in children

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