Acute haemorrhagic pancreatitis – A case of sudden death

Kanchan, Tanuj; Shetty, Mahabalesh; Nagesh, K.R.; Khadilkar, Urmila N; Shetty, B. Suresh Kumar; Menon, Anand; Menezes, Ritesh G.; Rastogi, Prateek

doi:10.1016/j.jflm.2008.08.006

Cited by 9 publications

(4 citation statements)

References 12 publications

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“…Sporadic case reports have linked acute haemorrhagic pancreatitis with sudden death although most of these did not occur during sleep and were associated with abdominal pain 24 25…”

Section: Discussionmentioning

confidence: 99%

A case control study on autopsy findings in sudden unexplained nocturnal death syndrome

Gervacio-Domingo

Lim²,

Reganit

et al. 2014

Heart Asia

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Aim Sudden unexplained nocturnal death syndrome (SUNDS) has been linked to the Brugada syndrome. In some places, acute haemorrhagic pancreatitis is widely held to cause it. We conducted a systematic, controlled autopsy study on Filipino SUNDS victims to rule out structural heart findings as well as acute haemorrhagic pancreatitis as causes. Methods and results A case control autopsy study was conducted comparing SUNDS victims between 18 and 50 years of age who died within 1 h of symptom onset with age-and gender-matched controls. There were 24 SUNDS (mean age 34.5 years) and 24 controls (mean 32.7 years). The autopsy incidence of structural heart disease was 8.3% (95% CI (1% to 27%)) and focal pancreatic haemorrhage was 4.17% (95% CI (0.1% to 20%)) but zero for true acute haemorrhagic pancreatitis among SUNDS victims. Autopsy findings in SUNDS versus controls were not significantly different from each other, showing no diagnostic abnormality in any of the organs. There was no significant difference in the incidence of acute haemorrhagic pancreatitis in both the SUNDS and control groups. We did not find fetal dispersion of the atrioventricular (AV) node, sclerosis or fibrosis of the AV conduction system, in a substudy of SUNDS cases. Conclusions We have shown that there is no significant difference in the overall autopsy findings between SUNDS and controls. Autopsy findings were normal in 70% of SUNDS; no cardiac structural pathology was found in 87% of cases. Haemorrhagic pancreatitis is the cause of death in a minority of SUNDS. The cardiac conduction system is normal in a subgroup of SUNDS studied.

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“…Sporadic case reports have linked acute haemorrhagic pancreatitis with sudden death although most of these did not occur during sleep and were associated with abdominal pain 24 25…”

Section: Discussionmentioning

confidence: 99%

A case control study on autopsy findings in sudden unexplained nocturnal death syndrome

Gervacio-Domingo

Lim²,

Reganit

et al. 2014

Heart Asia

View full text Add to dashboard Cite

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“…In acute pancreatitis, the most common extra-pancreatic pathology has been reported in the lung. The prevalence of pulmonary complications in autopsy studies ranges from 20% to 100%, pulmonary edema being the most common finding [4]. Cases of sudden death due to acute pancreatitis have been reported in the past where diagnosis could not be made until autopsy [5][6][7].…”

Section: Discussionmentioning

confidence: 99%

Fatal Acute Pancreatitis and Blood Alcohol Concentration. A Case Report and Literature Review

Mazzanti¹

2019

GJFSM

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Case report and literature review.Methods: This was a case report of a 54-year-old woman, with an history of chronic alcohol abuse, who was found dead at home. A packet of trazodone was found next to the woman and an autopsy was performed for suspected suicide. Literature regarding the epidemiology and social characteristics was searched from the PubMed database. Conclusion:Fatal acute pancreatitis occurring outside of the hospital concerns many patients who lived alone and in poor social conditions, and alcohol abuse is a common factor, also in the cause of death.

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“…The abdominal pain, which is the most frequent symptom, may vary widely in intensity from the typical sharp, incapacitating pain to mild bearable pain with a more or less asymptomatic onset. [11] AP is diagnosed based on clinical features, imaging studies, and laboratory investigation, the latter of which reveals elevated serum amylase and lipase concentrations at least 3 times higher than the normal levels. Additionally, an elevated serum creatinine concentration (>2.0 mg/dL) and blood glucose level (>250 mg/dL) are significant predictors of a fatal outcome, [12] as in the present case.…”

Section: Discussionmentioning

confidence: 99%

Severe acute hemorrhagic pancreatitis secondary to cholelithiasis as a rare cause of sudden unexpected death in medico-legal case

Srettabunjong

Limgitisupasin²

2016

Medicine

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Introduction:Acute pancreatitis (AP) is an uncommon disease with a wide clinical course varying from mild and self-limiting to severe with eventual death. However, death caused by AP is rare. Most cases of AP reported in the English-language literature are based on clinical data; few are medico-legal studies.Case presentation:The author recently experienced a case of sudden unexpected death in a young man caused by extensive severe hemorrhagic AP secondary to cholelithiasis, not chronic alcoholism, which is a much more prominent etiology of AP in medico-legal perspectives. The deceased had complained of dizziness, nausea, and fatigue without significant abdominal pain for about 1 week and received some home medications for symptomatic treatment including an antibiotic drug from a clinic just 2 days prior to his death. He had complained of lower extremity weakness, intense thirst, and subsequently collapsed and was brought to a nearby hospital where he was pronounced dead shortly after his admission following unsuccessful advanced cardiopulmonary resuscitation attempts.Conclusion:This case is herein reported with an extensive review of the pertinent literature to highlight the findings of the case and raise awareness within the medico-legal profession and also the medical profession.

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Acute haemorrhagic pancreatitis – A case of sudden death

Cited by 9 publications

References 12 publications

A case control study on autopsy findings in sudden unexplained nocturnal death syndrome

A case control study on autopsy findings in sudden unexplained nocturnal death syndrome

Fatal Acute Pancreatitis and Blood Alcohol Concentration. A Case Report and Literature Review

Severe acute hemorrhagic pancreatitis secondary to cholelithiasis as a rare cause of sudden unexpected death in medico-legal case

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