Acute haemorrhagic pericarditis: an unusual presentation of <i>Chlamydophila pneumoniae</i> pneumonia infection

Çelebi, Fatma Zehra Öztek; Fettah, Ali; Yeşil, Şule; Yoldaş, Tamer; Tanır, Gönül; Akçaboy, Meltem; Şenel, Saliha

doi:10.1080/20469047.2020.1728163

Cited by 1 publication

(3 citation statements)

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“…It should be mentioned that the patient presented a rather late serositis a few weeks after her discharge and remission of her initial symptoms. Indeed, similar limitations have been encountered in all relevant published studies (Table 1 ) [ 7 – 11 ]. These ‘inevitable’ limitations are somewhat expected in the setting of everyday clinical practice and real-world medicine.…”

Section: Discussionmentioning

confidence: 56%

“…Similar case reports are rare in the literature. Five studies have been identified [ 7 – 11 ]. Main characteristics of included studies are described in Table 1 .…”

Section: Discussionmentioning

confidence: 99%

“…The origin of the studies was Europe and Asia, while the prognosis of patients involved was good in most cases. The study by Oztek Celebi et al [ 7 ] was the only one where more than one antibody measurements were ordered (two in total), in order to investigate a similar case involving a 13-year-old boy with pericardial and bilateral pleural effusions. However, antibody titers did not clearly follow the expected kinetics.…”

Section: Discussionmentioning

confidence: 99%

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Chlamydia pneumoniae-associated pleuropericarditis: a case report and systematic review of the literature

et al. 2021

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Background Chlamydia pneumoniae is a common cause of atypical community acquired pneumonia (CAP). The diagnostic approach of chlamydial infections remains a challenge. Diagnosis of delayed chlamydial-associated complications, involving complex autoimmune pathophysiological mechanisms, is still more challenging. C. pneumoniae-related cardiac complications have been rarely reported, including cases of endocarditis, myocarditis and pericarditis. Case presentation A 40-year old female was hospitalized for pleuropericarditis following lower respiratory tract infection. The patient had been hospitalized for CAP (fever, dyspnea, chest X-ray positive for consolidation on the left upper lobe) 5 weeks ago and had received ceftriaxone and moxifloxacin. Four weeks after her discharge, the patient presented with fever, shortness of breath and pleuritic chest pain and was readmitted because of pericardial and bilateral pleural effusions (mainly left). The patient did not improve on antibiotics and sequential introduction of colchicine and methylprednisolone was performed. The patient presented impressive clinical and laboratory response. Several laboratory and clinical assessments failed to demonstrate any etiological factor for serositis. Chlamydial IgM and IgG antibodies were positive and serial measurements showed increasing kinetics for IgG. Gold standard polymerase chain reaction of respiratory tract samples was not feasible but possibly would not have provided any additional information since CAP occurred 5 weeks ago. The patient was discharged under colchicine and tapered methylprednisolone course. During regular clinic visits, she remained in good clinical condition without pericardial and pleural effusions relapse. Conclusions C. pneumoniae should be considered as possible pathogen in case of pleuritis and/or pericarditis during or after a lower respiratory tract infection. In a systematic review of the literature only five cases of C. pneumoniae associated pericarditis were identified. Exact mechanisms of cardiovascular damage have not yet been defined, yet autoimmune pathways might be implicated.

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Section: Discussionmentioning

confidence: 56%

“…Similar case reports are rare in the literature. Five studies have been identified [ 7 – 11 ]. Main characteristics of included studies are described in Table 1 .…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation