Acute heart failure registry from high-volume university hospital ED: comparing European and US data

Karásek, Jiří; Widimský, Petr; Ošťádal, Petr; Hrabakova, Hana; Pěnička, Martin

doi:10.1016/j.ajem.2011.03.027

Cited by 11 publications

(8 citation statements)

References 28 publications

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“…Social vulnerability has been confirmed to be an independent factor predicting the 1,000-day mortality in HF patients, and such patients have a number of factors that may lead to repeated admission and adverse outcomes after their discharge. The gender differences in characteristics among AHF patients have also been discussed in some previous reports (8-10). However, gender differences in the proportion of socially vulnerable patients and in the prognosis based on the presence of social vulnerability in AHF have not yet been reported.…”

Section: Introductionmentioning

confidence: 71%

Gender Differences in the Social Determinants of the Long-term Prognosis for Severely Decompensated Acute Heart Failure in Patients over 75 Years of Age

et al. 2019

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Objective The aim of present study was to elucidate the gender differences in social determinants among patients with acute heart failure (AHF). Methods A total of 1,048 AHF patients were enrolled, and the 508 AHF patients who were ! 75 years old and the 540 patients who were <75 years old were evaluated as the elderly and non-elderly cohorts, respectively. Participants who met one of the three marital status-, offspring-, and living status-related criteria were considered socially vulnerable, and subjects were thus classified into socially vulnerable and non-socially vulnerable groups by gender in both the non-elderly and elderly cohorts. Social vulnerability was significantly more common in the elderly cohort (n=246, 48.4%) than in the non-elderly cohort (n=197, 36.5%) and significantly more common in the elderly women (n=157, 69.4%) than in the elderly men (n=89, 31.5%). Kaplan-Meier curves showed that the survival rate of the socially vulnerable group was significantly poorer than that of the non-socially vulnerable group in the elderly male cohort (p=0.010). Social vulnerability was an independent predictor of the 1,000-day mortality in the elderly male cohort (hazard ratio: 1.942, 95% confidence interval: 1.102-3.422) but not in the elderly female cohort according to a multivariate analysis. Conclusion Social vulnerability was shown to be more common in elderly female AHF patients than in elderly men, although it was associated with a poor prognosis in elderly men. Reinforcing the social structure of elderly male AHF patients might help improve their prognosis.

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Section: Introductionmentioning

confidence: 71%

Gender Differences in the Social Determinants of the Long-term Prognosis for Severely Decompensated Acute Heart Failure in Patients over 75 Years of Age

et al. 2019

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“…Acute myocardial infarction (AMI) is a major cause of congestive heart failure 2. Therefore, alternative therapies to complement primary percutaneous coronary intervention (PCI) or thrombolytic therapy in the prevention of congestive heart failure after AMI are being investigated.…”

Section: Introductionmentioning

confidence: 99%

Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a meta-analysis of randomised controlled clinical trials

Delewi

Andriessen

Tijssen

et al. 2012

Heart

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“…Patients with de novo HF have no previous history or symptoms and signs of HF and present with their first manifestation of HF, whereas those with ADHF have pre-existing HF and present due to rapid worsening of their symptoms, usually in a decompensated state with fluid overload. Majority of patients with acute HF have coronary artery disease, hypertension and mitral regurgitation as their three main underlying conditions [10]. Although left ventricular systolic dysfunction is associated with acute HF patients, studies have shown that most of the patients with acute HF may have preserved systolic function with or without diastolic dysfunction.…”

Section: Renal Dysfunction In Acute Hfmentioning

confidence: 99%

“…Although left ventricular systolic dysfunction is associated with acute HF patients, studies have shown that most of the patients with acute HF may have preserved systolic function with or without diastolic dysfunction. Poor cardiac output as seen in most patients with acute HF is the main driving factor causing decreased renal perfusion and worsening renal function characterized as cardiorenal syndrome [10],[11]. Ronco et al .,[11] proposed the definition for cardiorenal syndrome as, “disorders of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other.” Furthermore, cardiorenal syndrome is classified into 5 types depending on which primary organ (heart or kidney) is affected first.…”

Section: Renal Dysfunction In Acute Hfmentioning

confidence: 99%

Cardiorenal biomarkers in acute heart failure

Choudhary¹,

Gopal²,

Kipper³

et al. 2012

Journal of Geriatric Cardiology

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Managing patients with heart failure (HF) is a challenging task within itself, but the presence of associated worsening renal function can greatly increase mortality and morbidity. Early diagnosis and treatment is the key to prevent re-hospitalizations and reduce healthcare costs. Biomarkers have long been established as highly sensitive and specific tools in diagnosing and prognosticating patients with HF. Reflecting distinct pathophysiological events and ongoing cellular insult, biomarkers have been proven superior to conventional laboratory tests. Availability of better assays and rapid analysis has allowed the use of biomarkers as point-of-care tests in the emergency department and at the patient's bed-side. Acute HF patients often go on to develop worsening renal function, termed as acute cardiorenal syndrome. The growing breadth of studies has shown the implications of combining multiple biomarkers to better chart outcomes and produce desirable results in such patients.

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Acute heart failure registry from high-volume university hospital ED: comparing European and US data

Cited by 11 publications

References 28 publications

Gender Differences in the Social Determinants of the Long-term Prognosis for Severely Decompensated Acute Heart Failure in Patients over 75 Years of Age

Gender Differences in the Social Determinants of the Long-term Prognosis for Severely Decompensated Acute Heart Failure in Patients over 75 Years of Age

Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a meta-analysis of randomised controlled clinical trials

Cardiorenal biomarkers in acute heart failure

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