Acute Hepatitis After Ingestion of Herbs

Shad, Javaid A.; Chinn, Colin; Brann, Oscar S.

doi:10.1097/00007611-199911000-00011

Cited by 37 publications

(18 citation statements)

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“…10,28,30 Careful investigation of the patient's pharmacologic history is essential in order to identify medications and herbal products associated with hepatotoxicity. 16,17,35 Acetaminophen-induced hepatic damage causes 54% and 16% of the cases of acute liver failure in the United Kingdom and United States respectively. 36 Although ischemic damage can be suspected on a clinical basis alone, and the patient history may suggest drug-or toxin-induced liver damage, there are no specific serologic tests for either condition, except in the case of acetaminophen poisoning, in which plasma acetaminophen levels may also represent a helpful guide to therapy.…”

Section: Marked and Moderate Aminotransferase Increasementioning

confidence: 99%

Liver enzyme alteration: a guide for clinicians

Giannini

Testa

Savarino

2005

Canadian Medical Association Journal

1,597

1,038

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ISOLATED ALTERATIONS OF BIOCHEMICAL MARKERS OF LIVER DAMAGE in a seemingly healthy patient can present a challenge for the clinician. In this review we provide a guide to interpreting alterations to liver enzyme levels. The functional anatomy of the liver and pathophysiology of liver enzyme alteration are briefly reviewed. Using a schematic approach that classifies enzyme alterations as predominantly hepatocellular or predominantly cholestatic, we review abnormal enzymatic activity within the 2 subgroups, the most common causes of enzyme alteration and suggested initial investigations.

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Section: Marked and Moderate Aminotransferase Increasementioning

confidence: 99%

Liver enzyme alteration: a guide for clinicians

Giannini

Testa

Savarino

2005

Canadian Medical Association Journal

1,597

1,038

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“…94 An estimated 500 herbal products are distributed worldwide, and are represented as harmless healthy products without side effects 95,96 Over 60% of patients in the U.S. being seen by a physician report use of herbal remedies. 97 Because herbal products are considered dietary supplements in many countries including the U.S., proof of efficacy and safety does not have to be provided by the manufacturer.…”

Section: Exposure To Herbal Toxinsmentioning

confidence: 99%

Sinusoidal Obstruction Syndrome (Hepatic Veno-Occlusive Disease)

Fan

Crawford

2014

Journal of Clinical and Experimental Hepatology

231

178

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“…A 69-year old US man was taking 14 tablets of a herbal mixture when he started experiencing anorexia, weight loss and jaundice [13]. He was admitted to hospital and diagnosed to suffer from toxic hepatitis.…”

Section: European Herbal Mixturesmentioning

confidence: 99%

Adverse effects of unconventional therapies in the elderly: A systematic review of the recent literature

Ernst

2002

AGE

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Unconventional therapies are increasingly popular, not least in populations of elderly individuals. This review summarizes the evidence regarding the risk unconventional therapies may entail for the elderly. Computerized literature searches were performed to locate all reports with original data on this topic. Most of the evidence found was anecdotal by nature and thus has obvious limitations. The results show that elderly patients can suffer harm from unconventional therapies. Herbal treatments are associated most frequently with adverse events. They can cause both direct toxicity and unwanted herb-drug interactions. Acupuncture, spinal manipulation and even massage therapy have also been implicated. Indirect risks exist if unconventional therapies are employed as a substitute for conventional treatments. It is concluded that unconventional therapies are not risk-free for elderly patients. All parties involved ought to be educated with a view of minimizing this risk, and more research is needed to increase our understanding of this area.

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Acute Hepatitis After Ingestion of Herbs

Cited by 37 publications

References 0 publications

Liver enzyme alteration: a guide for clinicians

Liver enzyme alteration: a guide for clinicians

Sinusoidal Obstruction Syndrome (Hepatic Veno-Occlusive Disease)

Adverse effects of unconventional therapies in the elderly: A systematic review of the recent literature

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