Acute hydrops in the corneal ectasias: associated factors and outcomes.

Large Penetrating Keratoplasty in the Management of Keratoglobus: A Case Report

“…Regarding the management of acute hydrops, it can be both conservative and invasive. Conventional treatment includes bandage contact lens, topical hypertonic saline and cycloplegics [3]. More invasive is the use of intracameral gas to tamponade the detached descemet's membrane to the posterior surface of the corneal stroma [4] [5].…”

“…Corneal thinning and fragility can result in corneal perforations, either spontaneous or following minor trauma. Spontaneous tears in Descemet's membrane may also occur, resulting in acute hydrops [1] [3].…”

Pneumodescemetopexy with perfluoroethane (C2F6) for the treatment of acute hydrops secondary to keratoconus

“…7,11 Despite its self-limiting nature, the time for resolution of corneal oedema may take up to 36 weeks when managed conventionally with topical medications with or without bandage contact lens. 12 Prolonged corneal oedema can potentially increase the risk of corneal neovascularisation, which is a significant risk factor for graft rejection, microbial keratitis, and corneal perforation. 7,13,14 Feder et al 13 reported that six (66.7%) of their patients with acute hydrops developed stromal neovascularisation when managed with topical medications.…”

Acute Corneal Hydrops in Down Syndrome

“…On slit lamp examination, the conjunctiva may be injected and a diffuse stromal opacity may be noted in the cornea. This condition, referred to as acute corneal hydrops, is caused by the rupture of Descemet's membrane, followed by an influx of aqueous humor into the weakened corneal stroma that leads to a marked edema and the formation of cystic spaces [1,3,4]. The edema may persist for weeks or months, usually diminishing gradually, with relief of pain and resolution of the redness and corneal edema ultimately being replaced by scarring [1].…”