Acute inspiratory stridor: a presentation of myasthenia gravis

Matin, Mohammad A.; Alam, Khurshid; O’Driscoll, Kieran; Murphy, Patrick J.

doi:10.1017/s0022215100158050

Cited by 6 publications

(3 citation statements)

References 13 publications

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“…Unusual presentations such as vocal cord paralysis have been described as the initial manifestation of both seropositive and seronegative myasthenia gravis patients. [1][2][3][4] In some patients, a precipitating factor such as surgery with use of depolarizing drugs could be identified as a trigger, whereas no precipitating cause could be ascertained in others. In all these reports, patients were not diagnosed and treated for myasthenia prior to the presentation of vocal cord paralysis.…”

Section: Discussionmentioning

confidence: 99%

Isolated vocal cord paralysis mimicking respiratory weakness in MuSK myasthenia

Paramasivan¹,

Vysakha²,

Narayan³

et al. 2022

NeuroAsia

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Vocal cord paralysis is a rare manifestation of myasthenia gravis and challenging to diagnose with presentations other than stridor. We discuss a patient with MuSK myasthenia gravis who had respiratory difficulty due to vocal cord palsy and the diagnostic difficulties encountered in establishing the etiology for the dyspnea. The diagnosis was captured by spirometry flow volume loop showing flattening of the inspiratory portion suggestive of extrathoracic upper airway obstruction. Early diagnosis can prevent the need for tracheostomy and other emergent measures.

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Section: Discussionmentioning

confidence: 99%

Isolated vocal cord paralysis mimicking respiratory weakness in MuSK myasthenia

Paramasivan¹,

Vysakha²,

Narayan³

et al. 2022

NeuroAsia

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“…They may present with stridor. [6][7][8] The vocal cords of our patient was also involved by the disease as she already had a speech problem.…”

Section: Discussionmentioning

confidence: 99%

An undiagnosed myasthenia gravis presenting as isolated recurrent acute respiratory failure

Sharma

Yeolekar

2012

Journal of Neurosciences in Rural Practice

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Acute respiratory failure is an uncommon initial presentation of myasthenia gravis (MG). In our case a 22-year-old woman of unrecognized MG presented to the emergency department with isolated respiratory failure as the first presenting symptom. Initially she presented with dysphonia and was managed by speech therapist and ENT surgeons for 3 months. Subsequently, she presented with signs and symptoms of sepsis and went into acute respiratory failure. This case highlights the need to consider MG in the differential diagnosis of an otherwise unexplained respiratory failure in the critical care setting.

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“…They may present with stridor. [5][6][7] Some authors suggested to perform flow volume loops in all myasthenic patients as a screening test. 8 The vocal cord of our patient was also involved by the disease as she already had speech problem.…”

Section: Discussionmentioning

confidence: 99%