Acute intramural hematoma of the aorta: A mystery in evolution

Acute aortic dissection (AAD) is the most common aortic catastrophe. The mortality rate of type A dissection approaches 40% to 50% in 48 hours. Causes of death include rupture, aortic insufficiency, or malperfusion involving the coronary arteries, head vessels, visceral arteries, and lower extremities. Other acute aortic conditions can be confused with AAD. Emergent surgery is usually recommended, although there are some situations in which initial management of malperfusion or conservative therapy can be considered prior to proximal aortic repair. Various surgical techniques are employed to manage AAD. This article reviews the etiology, clinical presentations, and management of patients with type A AAD.

show abstract

“…The IRAD reports 58/1040 (5.7%) dissections were, in fact, IMHs. 29 Song et al, 30 however, reported a 28.3% rate of IMHs in their series.…”

Section: Differential Diagnosis Of Taadmentioning

confidence: 87%

Diagnosis and Management of Acute Type A Aortic Dissection

Hines

Dracea²,

Katz³

2011

Cardiology in Review

View full text Add to dashboard Cite

show abstract

“…With an FDR of 0 and by applying a minimal fold change of 2, the analyses revealed consistent patterns of differential gene expression. Thus, a total of 623 genes were found to show 302 Vascular and Endovascular Surgery 46 (4) altered expression in patients with type B AD compared with controls, of which 220 genes were upregulated and 403 genes were downregulated ( Figure 2B). …”

Section: Microarray Analysismentioning

confidence: 99%

“…It is proposed that bleeding of the vasa vasorum represents the first step of dissection process. 3,4 The Stanford classification distinguishes AD into type A or type B, depending on whether the site of the initial tear is in the ascending or descending arms of the aorta, respectively. Almost 60% of reported cases of AD are type A and 40% type B.…”

Section: Introductionmentioning

confidence: 99%

Gene Expression Profiling in Acute Stanford Type B Aortic Dissection

Wang

Yao

Guo

et al. 2012

Vasc Endovascular Surg

View full text Add to dashboard Cite

show abstract

“…Its true incidence is difficult to determine but is estimated to vary between 2% and 8% of all acute aortic syndromes. [2][3][4] According to the classification by Svensson et al 5 (Table), PAU and IMH can be considered as variants of the classical double-barrel aortic dissection. They occur more often in the descending aorta as opposed to classical dissections.…”

Section: ¤ ¤mentioning

confidence: 99%