2018
DOI: 10.1111/ene.13874
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Acute ischaemic lesions are associated with cortical superficial siderosis in spontaneous intracerebral hemorrhage

Abstract: Background and purpose Diffusion‐weighted imaging (DWI) commonly detects acute ischaemic lesions in patients with acute intracerebral hemorrhage (ICH), especially with cerebral amyloid angiopathy (CAA). We investigated the relationship between cortical superficial siderosis (cSS), a neuroimaging marker of CAA, and DWI lesions in patients with acute ICH. Methods We conducted a retrospective analysis of prospectively collected data from consecutive patients with acute supratentorial ICH who underwent brain magne… Show more

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Cited by 12 publications
(10 citation statements)
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“…MR images were acquired on 1.5-T or 3-T scanners and included at least T2 * -weighted gradient recalled echo (T2 * -GRE) and axial fluid-attenuated inversion recovery (FLAIR) sequences, as previously described (11). Among the 260 patients with CMB included in the analysis, 148 (56.9%) underwent a 3-T MRI and 112 (43.1%) a 1.5-T MRI.…”
Section: Methodsmentioning
confidence: 99%
“…MR images were acquired on 1.5-T or 3-T scanners and included at least T2 * -weighted gradient recalled echo (T2 * -GRE) and axial fluid-attenuated inversion recovery (FLAIR) sequences, as previously described (11). Among the 260 patients with CMB included in the analysis, 148 (56.9%) underwent a 3-T MRI and 112 (43.1%) a 1.5-T MRI.…”
Section: Methodsmentioning
confidence: 99%
“…We found a RDWIL prevalence of 23.5%, slightly higher than the 19% reported in a landmark 2019 meta-analysis, 3 reflecting the inclusion of recent prospective studies. 2,[4][5][6][7]10,22 We also report novel associations that provide insight into potential mechanisms underlying RDWILs. According to our meta-analysis, RDWILs are frequently observed in the first 48 hours, but new RDWILs may still be detected beyond day 7 and as late as 1 month, 13,17 implying they result from an ongoing process, namely cerebral small vessel disease.…”
Section: Rdwil Number and Locationmentioning
confidence: 71%
“…RDWILs were multiple in 68.8% patients (mean: 3.8) and contralateral to the ICH in 46.4%, mostly located within the cortex or subcortically (52.2% and 51.9% respectively; Table S5). 1,2,10,12,13,15,17,19–21…”
Section: Resultsmentioning
confidence: 99%
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“…IRIS is a condition that occurs in immunosuppression or AIDS cases. The immune system recovers after treatment, but then responds to previously acquired opportunistic infections with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse (12). The mechanism of IRIS is thought to be due to a switch from following initiation therapy from a predominantly Th2 immune response (anti-inflammatory) to a Th1 or proinflammatory response.…”
Section: Discussionmentioning
confidence: 99%