2019
DOI: 10.1016/s0140-6736(19)32563-2
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Acute kidney injury

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Cited by 1,237 publications
(1,025 citation statements)
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References 169 publications
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“…Despite enormous advances in treatment of patients suffering from acute kidney injury, we still encounter a high morbidity and mortality rate. Hence, effective approaches for prevention and treatment are still lacking [1,2], with only limited and unsatisfactory therapeutic options. Fortunately, the kidney has the intrinsic capacity to recover from ischemic or toxic insults that cause renal cell death [3].…”
Section: Introductionmentioning
confidence: 99%
“…Despite enormous advances in treatment of patients suffering from acute kidney injury, we still encounter a high morbidity and mortality rate. Hence, effective approaches for prevention and treatment are still lacking [1,2], with only limited and unsatisfactory therapeutic options. Fortunately, the kidney has the intrinsic capacity to recover from ischemic or toxic insults that cause renal cell death [3].…”
Section: Introductionmentioning
confidence: 99%
“…Contrast-associated AKI is becoming less frequent because of reduced toxicity and lesser amounts of contrast media used for imaging techniques. However, prevention measures should still be considered for individual patients, especially in patients with CKD [2].…”
Section: Aki Preventionmentioning
confidence: 99%
“…Acute kidney injury (AKI) is a highly complicated clinical disorder that is widely characterized by rapid rate of reduced rate of glomerular filtration (GFR), demonstrated by a rise in serum creatinine (SCr) concentration or oliguria, or both [1][2][3][4][5]. AKI is common among hospitalized patients, affecting approximately 10%-20% of hospitalized patients, of whom 10% require renal replacement therapy (RRT) [6][7][8][9][10][11].…”
Section: Introductionmentioning
confidence: 99%
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“…Among critically ill patients, sepsis is thought to be the most common cause of severe AKI [5,6]. Septic acute kidney injury (AKI), identified when both sepsis and AKI present, is a syndrome of acute function impairment and organ damage, accounting for ~ 50% AKI in ICU (Intensive Care Unit) [7,8]. The hospital mortality is 47% and 1-year survival is only 77% for patients with stage 2-3 AKI lack of resolution within 7 days [8].…”
Section: Introductionmentioning
confidence: 99%