Acute Kidney Injury in Hypotensive Trauma Patients Following Resuscitative Endovascular Balloon Occlusion of the Aorta Placement

Hunt, Iris; Gold, Logan; Hunt, John P.; Marr, Alan B.; Greiffenstein, Patrick; Stuke, Lance; Smith, Alison F.

doi:10.1177/00031348231157894

Cited by 9 publications

(2 citation statements)

References 18 publications

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“…Remarkably, patients treated with pREBOA had a significantly lower AKI incidence at 6.7% compared with those treated with ER-REBOA at 40%. 57 …”

Section: Resultsmentioning

confidence: 99%

Complications associated with the use of resuscitative endovascular balloon occlusion of the aorta (REBOA): an updated review

Fontenelle Ribeiro Junior,

Salman,

Al-Qaraghuli

et al. 2024

Trauma Surg Acute Care Open

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Resuscitative endovascular balloon occlusion of the aorta (REBOA) has become part of the arsenal to temporize patients in shock from severe hemorrhage. REBOA is used in trauma to prevent cardiovascular collapse by preserving heart and brain perfusion and minimizing distal hemorrhage until definitive hemorrhage control can be achieved. Significant side effects, including death, ischemia and reperfusion injuries, severe renal and lung damage, limb ischemia and amputations have all been reported. The aim of this article is to provide an update on complications related to REBOA. REBOA has emerged as a critical intervention for managing severe hemorrhagic shock, aiming to temporize patients and prevent cardiovascular collapse until definitive hemorrhage control can be achieved. However, this life-saving procedure is not without its challenges, with significant reported side effects. This review provides an updated overview of complications associated with REBOA. The most prevalent procedure-related complication is distal embolization and lower limb ischemia, with an incidence of 16% (range: 4–52.6%). Vascular and access site complications are also noteworthy, documented in studies with incidence rates varying from 1.2% to 11.1%. Conversely, bleeding-related complications exhibit lower documentation, with incidence rates ranging from 1.4% to 28.6%. Pseudoaneurysms are less likely, with rates ranging from 2% to 14%. A notable incidence of complications arises from lower limb compartment syndrome and lower limb amputation associated with the REBOA procedure. Systemic complications include acute kidney failure, consistently reported across various studies, with incidence rates ranging from 5.6% to 46%, representing one of the most frequently documented systemic complications. Infection and sepsis are also described, with rates ranging from 2% to 36%. Pulmonary-related complications, including acute respiratory distress syndrome and multisystem organ failure, occur in this population at rates ranging from 7.1% to 17.5%. This comprehensive overview underscores the diverse spectrum of complications associated with REBOA.

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“…Remarkably, patients treated with pREBOA had a significantly lower AKI incidence at 6.7% compared with those treated with ER-REBOA at 40%. 57 …”

Section: Resultsmentioning

confidence: 99%

Complications associated with the use of resuscitative endovascular balloon occlusion of the aorta (REBOA): an updated review

Fontenelle Ribeiro Junior,

Salman,

Al-Qaraghuli

et al. 2024

Trauma Surg Acute Care Open

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“…[44,45] In addition, recent evidence showed pREBOA had a significantly lower incidence of developing an AKI compared to routine REBOA in the United States. [46] 3.3.2. Application of portable ultrasonic devices.…”

Section: 31mentioning

confidence: 99%

Common complications and prevention strategies for resuscitative endovascular balloon occlusion of the aorta: A narrative review

Guan,

Chen,

Zhou

et al. 2023

Medicine

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Resuscitative endovascular balloon occlusion of the aorta (REBOA) is considered a key measure of treatment due to its use in stabilizing patients in shock through temporary inflow occlusion for noncompressible torso hemorrhage as well as its supportive role in myocardial and cerebral perfusion. Although its clinical efficacy in trauma has been widely recognized, concerns over related complications, such as vascular access and ischemia-reperfusion, are on the rise. This paper aims to investigate complications associated with REBOA and identify current and emerging prevention or mitigation strategies through a literature review based on human or animal data. Common complications associated with REBOA include ischemia/reperfusion injuries, vessel injuries, venous thromboembolism, and worsening proximal bleeding. REBOA treatment outcomes can be improved substantially with the help of precise selection of patients, better visualization tools, improvement in balloon catheters, blockage strategies, and medication intervention measures. Better understanding of REBOA-related complications and further research on the strategies to mitigate the occurrence of such complications will be of vital importance for the optimization of the clinical outcomes in patients.

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Resuscitative endovascular balloon occlusion of the aorta provides better survival outcomes for noncompressible blunt torso bleeding below the diaphragm compared to resuscitative thoracotomy

Liao,

Huang,

Hsu

et al. 2025

Injury

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Acute Kidney Injury in Hypotensive Trauma Patients Following Resuscitative Endovascular Balloon Occlusion of the Aorta Placement

Cited by 9 publications

References 18 publications

Complications associated with the use of resuscitative endovascular balloon occlusion of the aorta (REBOA): an updated review

Complications associated with the use of resuscitative endovascular balloon occlusion of the aorta (REBOA): an updated review

Common complications and prevention strategies for resuscitative endovascular balloon occlusion of the aorta: A narrative review

Resuscitative endovascular balloon occlusion of the aorta provides better survival outcomes for noncompressible blunt torso bleeding below the diaphragm compared to resuscitative thoracotomy

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