Acute Kidney Injury in Patients With Normal Renal Function Undergoing Transcatheter or Surgical Aortic Valve Replacement: Should We Be Concerned?

Azzalini, Lorenzo; Moroni, Francesco

doi:10.1016/j.cjca.2020.04.022

Cited by 1 publication

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many factors play a role in the development of AKI after TAVI. Hemodynamic changes such as the development of hypotension during the procedure, prolonged procedure and bleeding along with inflammatory and nephrotoxic causes (amount of contrast material) are some of the factors that cause kidney damage [ 10 ]. Among other patient-specific risk factors, advanced age, female gender, diabetes mellitus, hypertension, presence of chronic kidney disease, and presence of anemia before and after the procedure are independent risk factors for development of AKI after TAVI [ 11 – 13 ].…”

Section: Discussionmentioning

confidence: 99%

Factors associated with acute kidney injury in patients undergoing transcatheter aortic valve implantation: Short-term outcomes and impact of right heart failure

Aslan Kutsal

2024

North Clin Istanbul

View full text Add to dashboard Cite

OBJECTIVE Transcatheter aortic valve implantation (TAVI) was developed as an alternative to surgery for symptomatic, high-risk patients with severe aortic stenosis (AS). Acute kidney injury, a major complication of TAVI, is associated with a poor prognosis. In our study, we planned to investigate the effect of right heart failure on the development of acute kidney injury after TAVI and other factors contributing to the development of AKI. METHODS Between January 2015 and December 2020, 198 patients who underwent TAVI due to severe symptomatic aortic stenosis at Dr. Siyami Ersek Cardiovascular Surgery Hospital were screened. Local ethics committee approval was obtained (HNEAH-KAEK 2021/134-3343). Transthoracic echocardiographic findings and laboratory evaluations were recorded. Patients were evaluated according to Acute Kidney Injury Network (AKIN) criteria. RESULTS The rate of AKI after TAVI was found to be 41.9%. The mean age of patients who developed AKI was higher (80.90±6.8). AKI development rates were higher in the female gender (68.7%) and patients with hypertension (44.8%). It was observed that the risk of developing AKI was higher in patients who underwent TAVI and developed AKI afterwards, especially in patients with stage-3 and stage-4 advanced CKD before TAVI (p<0.01) We did not find an independent relationship between AKI and right-heart failure in our analysis. CONCLUSION We observed that chronic kidney disease before TAVI, advanced age, and female gender are important determinants of the development of AKI after TAVI. Although a relationship between TAVI and right heart failure has not been demonstrated, large-scale studies are needed in the future.

show abstract

Section: Discussionmentioning

confidence: 99%

Factors associated with acute kidney injury in patients undergoing transcatheter aortic valve implantation: Short-term outcomes and impact of right heart failure

Aslan Kutsal

2024

North Clin Istanbul

View full text Add to dashboard Cite

show abstract

Acute Kidney Injury in Patients With Normal Renal Function Undergoing Transcatheter or Surgical Aortic Valve Replacement: Should We Be Concerned?

Cited by 1 publication

References 23 publications

Factors associated with acute kidney injury in patients undergoing transcatheter aortic valve implantation: Short-term outcomes and impact of right heart failure

Factors associated with acute kidney injury in patients undergoing transcatheter aortic valve implantation: Short-term outcomes and impact of right heart failure

Contact Info

Product

Resources

About