Acute Kidney Injury in Pediatric Diabetic Ketoacidosis

Incidence and factors associated with acute kidney injury among children with type 1 diabetes hospitalized with diabetic ketoacidosis: A prospective study

“…The 13 reported that AKI was found in 56.5% of children with DKA. Higher frequencies of AKI were reported by Hursh et al 2 and Yang et al 15 who found that the incidences of AKI among children with DKA were 64.2% and 77.7%, respectively. On the other hand, Weissbach et al 12 and Baalaaji et al 11 found that 30% and 35.3% of children with DKA developed AKI, respectively.…”

“…Identification of factors associated with AKI might allow early detection of patients at increased risk for AKI development and help to prevent the progression of severe AKI among those patients 26 . Previous studies found that several factors were associated with AKI development among children with DKA 2,11–15 . The effects of these factors might be explained by the consequences of severe dehydration 12 .…”

“…A few previous retrospective studies assessed AKI in children with DKA. These studies reported that AKI was frequent among children hospitalized with DKA and that about 30%–78% of DKA episodes in children were associated with AKI development 2,11–15 …”

“…These studies reported that AKI was frequent among children hospitalized with DKA and that about 30%-78% of DKA episodes in children were associated with AKI development. 2,[11][12][13][14][15] This study aimed to prospectively assess the incidence and factors associated with AKI development among T1DM children hospitalized with DKA using the KDIGO criteria.…”

Acute Kidney Injury in Children with Diabetic Ketoacidosis: Risk Factors and Outcome

“…In this issue of Indian Journal of Pediatrics, the article by Yang et al [8] reported 90 episodes of DKA in 58 children with Type1DM and AKI was present in a total of 70 hospitalizations (77.8%); of these 20% had stage 1 and 57.7% had stage 2 and 3. The proportion of cases with AKI decreased over 12 h (47.4%) and 24 h (28.3%) of hospitalization following treatment.…”