2022
DOI: 10.1038/s41541-022-00445-5
|View full text |Cite
|
Sign up to set email alerts
|

Acute kidney rejection after anti-SARS-CoV-2 virus-vectored vaccine—case report

Abstract: COVID-19 infection remains a threat to the health systems of many countries. Potential success in the fight against the COVID-19 pandemic is the vaccination of high-risk groups, including patients with end-stage kidney disease (ESKD) and after solid organ transplantation (SOT). Immunosuppression in kidney transplant recipients can also reduce the immunogenicity of SARS-CoV-2 vaccines (varied by vaccine platform), available data suggest that they are efficacious in approximately 50–70%, compared to non-transpla… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
14
0

Year Published

2022
2022
2024
2024

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 7 publications
(14 citation statements)
references
References 14 publications
0
14
0
Order By: Relevance
“…Cells in the anterior chamber There were 42 case reports [5][6][7][8][11][12][13]17,18,[20][21][22][24][25][26][27][29][30][31][32][33][34][35][37][38][39][40][41][42][43][44][45][48][49][50][51][52][53][54][55][56][57], 8 case series [9,10,14,28,36,46,47,58] and 2 cohort studies [19,23]. These studies were conducted in t...…”
Section: Study Characteristics and Qualitymentioning
confidence: 99%
See 2 more Smart Citations
“…Cells in the anterior chamber There were 42 case reports [5][6][7][8][11][12][13]17,18,[20][21][22][24][25][26][27][29][30][31][32][33][34][35][37][38][39][40][41][42][43][44][45][48][49][50][51][52][53][54][55][56][57], 8 case series [9,10,14,28,36,46,47,58] and 2 cohort studies [19,23]. These studies were conducted in t...…”
Section: Study Characteristics and Qualitymentioning
confidence: 99%
“…There were reports of fifty-six organ rejection cases following COVID-19 vaccination (fifty-one new-onset cases [5][6][7][8][9][39][40][41][42][43] and five relapsed cases [5,9,36,38]) (see Table 1). Allograft rejections after COVID-19 vaccination occurred for cornea (n = 38, 67.8%) [5,8,17,[20][21][22][23][24][28][29][30][31][32][33][34][35]37,38,42,43], liver (n = 11, 19.6%) [9,25,36,39,41], kidney (n = 6, 10.7%) [6,7,18,19,26,40] and pancreas (n = 1, 1.8%) [27] transplant recipients.…”
Section: Meta-analysis Of Organs Rejection Following Covid-19 Vaccina...mentioning
confidence: 99%
See 1 more Smart Citation
“…The fear of suboptimal immune response is often accompanied by the fear of severe adverse events in SOT recipients ( 22 ). Although the benefit of COVID-19 vaccination outweighs the risk of adverse events, several acute rejections have been reported in SOT recipients which raises a number of safety concerns ( 23 25 ). On the other hand, most of the COVID-19 studies in SOT recipients show no association between the vaccination and the development of organ rejection ( 22 ).…”
Section: Introductionmentioning
confidence: 99%
“…The mechanisms by which immunosuppression might alter lymphocyte function in this population remains unclear. An additional wrinkle in the plot is the risk of inducing an acute rejection episode due to the heterogeneity of the immune response and possible cross reactivity ( 78 , 79 ).…”
Section: Sars Cov-2 Mrna Vaccinationmentioning
confidence: 99%