Acute leg ischaemia as a presentation of hyperleukocytosis syndrome in acute myeloid leukaemia

Abstract

a manifestation of lymphoma, and all died before receiving chemotherapy. If a patient with WM develops ascites, clinicians should consider the possibility that the disease has transformed into IL, especially if the patient has received alkylating agents.

Recurrent Ischemic Cerebrovascular Accidents with Recurrent Acute Ischemia of the Left Upper Limb Revealing Acute Myeloid Leukemia

“…In the postoperative period, the risk of recurrence is high. So, the chemotherapy must be started as soon as the diagnosis is done [11,15,16]. It reduces the rate of blasts in the blood, and reduces the risk of recurrence of embolism [12].…”

Calf pain: Atypical presentation of acute lymphoblastic leukemia mimicking deep venous thrombosis

“…Hyperleukocytosis often causes symptomatic occlusion of the microvasculature (leukostasis), resulting in ischemia, hemorrhage, and edema of the involved organs. Central nervous system deterioration leading to coma, splenic infarction, myocardial ischemia, acute tubular necrosis and priapism are the most commonly reported complications 9,10 …”

“…Central nervous system deterioration leading to coma, splenic infarction, myocardial ischemia, acute tubular necrosis and priapism are the most commonly reported complications. 9,10 Lower extremities involvement is not a common presentation of hyperleukocytosis and was reported anecdotally in the literature only in adult cases of acute myeloid leukemia with severe hyperleukocytosis. 10,11 Its presence is usually diagnosed empirically when a patient with leukemia and a white blood cell over 100 000/mm 3 presents with symptoms thought to be due to tissue hypoxia.…”

How we approach a patient with symptoms of leukostasis requiring emergent leukocytapheresis

“…Pulmonary complications include dyspnea, tachypnea, hypoxemia, diffuse alveolar hemorrhage, and respiratory failure . Rare manifestations also include acute leg ischemia, renal vein thrombosis, and priapism …”