Acute Limb Ischemia in a Patient With COVID-19 Pneumonia

Nasir, Shahbaz Ali; Arif, Anum; Shahid, Mubasshar; Ahmed, Yashfeen; Riaz, Bismah; Sherwani, Nawabzada Zeerak Farhat

doi:10.7759/cureus.18574

Cited by 3 publications

(5 citation statements)

References 18 publications

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“…Similar case was reported in Pakistan, Lahore, where an elderly patient with comorbidities presented with fever and lower leg discoloration in which became a non-salvageable limb and required subsequent amputation of the affected limb [ 2 ].…”

Section: Discussionsupporting

confidence: 66%

“…Although respiratory symptoms predominate in patients with COVID-19, thrombosis can also occur. There have been reports of ALI observed mostly among adults with comorbidities [ 2 – 5 , 7 ] and only one case has been reported in an adolescent [ 6 ], but to our knowledge, no cases at the time of writing of this case has been reported in younger age groups. This is the first reported case of a four-year-old with ALI due to COVID-19.…”

Section: Discussionmentioning

confidence: 87%

“…Several recently published articles have reported the occurrence of arterial thrombotic events in COVID-19-positive patients with no history of peripheral arterial disease [ 2 , 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which was discovered in December 2019 and was declared a pandemic by the World Health Organization (WHO) on March 2020 [ 1 ]. Since December 2019, when the first case of coronavirus disease was reported, there has been a constant evolution in the clinical presentation of the disease from simple viral-like illnesses such as fever, sore throat, and myalgia to Acute Respiratory Distress Syndrome (ARDS), multiple organ failure, and microthrombosis [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

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A rare complication of acute lower limb ischemia post coronavirus disease 2019 infection in a healthy pediatric patient: case report

Badr,

AlSofyani,

AlGoraini

2023

BMC Pediatr

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Background Coronavirus Disease 2019 (COVID-19) is a novel respiratory disease that first emerged in 2019. Patients infected with this disease present with a myriad of symptoms. Limb ischemia and hypercoagulability are complications identified in adults. COVID-19-related vasculitis is a known but seldom reported complication in pediatric patients, and the treatment approach is still not well established. Case presentation We report the case of a healthy four-year-old female with a history of COVID-19 who developed acute lower limb ischemia. This was initially treated as a case of acute snake envenomation by administering snake antivenom with no improvement. She eventually developed lower limb acrocyanosis with an inability to ambulate. The patient was started on interleukin-6 receptor inhibitors (tocilizumab), anticoagulants, and pulse steroid therapy. The patient had complete resolution with the loss of only one toe. Conclusion Identification of thromboembolic complications in pediatric patients with no comorbidities and a history of COVID-19 can be difficult. Early recognition and treatment have a major impact on morbidity and can increase the likelihood of limb salvage.

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Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 87%

“…Several recently published articles have reported the occurrence of arterial thrombotic events in COVID-19-positive patients with no history of peripheral arterial disease [ 2 , 3 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A rare complication of acute lower limb ischemia post coronavirus disease 2019 infection in a healthy pediatric patient: case report

Badr,

AlSofyani,

AlGoraini

2023

BMC Pediatr

View full text Add to dashboard Cite

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“…1 An acute limb ischemia may present in the form of chilblains, bullae, acral cyanosis, bruising, blood blisters, acute limb ischemia and lifethreatening gangrene. [4][5][6] Shao et al reported that an acute upper limb ischemia may be the first manifestation of COVID-19 infection. 7 In a review of 27 studies including 5 cohorts, 5 case series, and 17 case reports, Cheruiyot et al found that arterial thrombosis had occurred in about 4% of critically ill COVID-19 patients which could affect multiple arteries.…”

Section: Iranian Medicinementioning

confidence: 99%

Subclavian Artery Thrombosis in a COVID-19 Patient

2022

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Associations between SARS-CoV-2 infections and thrombotic complications necessitating surgical intervention: A systematic review

Ferraro¹,

Reynolds²,

Edoigiawerie³

et al. 2022

World J Methodol

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BACKGROUND Several unique clinical features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19) infection, have been identified and characterized. One such feature, mostly among patients with severe COVID-19 infection, has become known as COVID-19-induced coagulopathy. Surgical patients with a history of or active COVID-19 infection bear a significantly higher risk for postoperative thrombotic complications. These patients may require surgical intervention to treat severe thrombotic complications. Few studies have been carried out to better characterize this association. The purpose of this study was to perform a systematic review and meta-analysis of the literature on COVID-19 infections that led to thrombotic complications necessitating surgical intervention. We hypothesized that patients with recent or active COVID-19 infection would have high rates of thromboembolic complications both arterial and venous in origin. AIM To perform a systematic review and meta-analysis of the literature on COVID-19 infections that led to thrombotic complications necessitating surgical intervention. METHODS The current systematic review implemented an algorithmic approach to review all the currently available English medical literature on surgical interventions necessitated by COVID-19 thrombotic complications using the preferred reporting items for systematic reviews and meta-analysis principles. A comprehensive search of the medical literature in the “PubMed”, “Scopus”, “Google Scholar” top 100 results, and archives of Plastic and Reconstructive Surgery was performed using the key words “COVID-19” AND “surgery” AND “thromboembolism” AND “complication”. The search string was generated and the records which were not specific about surgical interventions or thrombotic complications due to COVID-19 infection were excluded. Titles and abstracts were screened by two authors and full-text articles were assessed for eligibility and inclusion. Finally, results were further refined to focus on articles that focused on surgical interventions that were necessitated by COVID-19 thrombotic complications. RESULTS The database search resulted in the final inclusion of 22 retrospective studies, after application of the inclusion/exclusion criteria. Of the included studies, 17 were single case reports, 3 were case series and 2 were cross sectional cohort studies. All studies were retrospective in nature. Twelve of the reported studies were conducted in the United States of America, with the remaining studies originating from Italy, Turkey, Pakistan, France, Serbia, and Germany. All cases reported in our study were laboratory confirmed SARS-CoV-2 positive. A total of 70 cases involving surgical intervention were isolated from the 22 studies included in this review. CONCLUSION There is paucity of data describing the relationship...

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Acute Limb Ischemia in a Patient With COVID-19 Pneumonia

Cited by 3 publications

References 18 publications

A rare complication of acute lower limb ischemia post coronavirus disease 2019 infection in a healthy pediatric patient: case report

A rare complication of acute lower limb ischemia post coronavirus disease 2019 infection in a healthy pediatric patient: case report

Subclavian Artery Thrombosis in a COVID-19 Patient

Associations between SARS-CoV-2 infections and thrombotic complications necessitating surgical intervention: A systematic review

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