2021
DOI: 10.1016/j.jemermed.2021.01.004
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Acute Liver Injury After Long-Term Herbal “Liver Cleansing” and “Sleep Aid” Supplement Use

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Cited by 5 publications
(3 citation statements)
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“…7 The HDS-DILI can be not only severe, leading to hepatocellular injury with jaundice, but also fatal, leading to death or liver transplantation. [31][32][33][34][35][36][37] Kesar et al 35 The prevalence of the use of potentially hepatotoxic botanical products rather than use of benign, non-hepatotoxic HDSs, such as vitamins and minerals, has not been systematically studied nor reported. The present study found that between January 2017 and March 2020, approximately 15 million US adults consumed at least 1 potentially hepatotoxic botanical product within the past 30 days, which was comparable to the number of people taking potentially hepatotoxic prescription drugs, such as simvastatin, NSAIDs, and sertraline (Figure 2).…”
Section: Discussionmentioning
confidence: 99%
“…7 The HDS-DILI can be not only severe, leading to hepatocellular injury with jaundice, but also fatal, leading to death or liver transplantation. [31][32][33][34][35][36][37] Kesar et al 35 The prevalence of the use of potentially hepatotoxic botanical products rather than use of benign, non-hepatotoxic HDSs, such as vitamins and minerals, has not been systematically studied nor reported. The present study found that between January 2017 and March 2020, approximately 15 million US adults consumed at least 1 potentially hepatotoxic botanical product within the past 30 days, which was comparable to the number of people taking potentially hepatotoxic prescription drugs, such as simvastatin, NSAIDs, and sertraline (Figure 2).…”
Section: Discussionmentioning
confidence: 99%
“…Further, although the safety of turmeric and curcumin has been well established, recent reports of isolated cases of HILI have been noted. Koenig et al [39] described a 53-year-old woman who developed jaundice after a monthlong use of a combination herbal "liver-cleansing" compound and a nightly herbal "sleep aid." The "Liver Detoxifier and Regenerator" listed turmeric root as one of its many ingredients.…”
Section: Turmeric/curcuminmentioning
confidence: 99%
“…The table below (Table 11) is a summary of published case reports with key information retrieved to demonstrate the circumstances behind the adverse events attributed to herbal supplements [123][124][125][126][127][128][129][130][131][132][133][134][135].…”
Section: Case Reports Showcasing the Health Hazards Of Herbsmentioning
confidence: 99%