Acute macular neuroretinopathy associated with COVID-19 infection

David, James A; Fivgas, George D.

doi:10.1016/j.ajoc.2021.101232

Cited by 25 publications

(22 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most frequently observed signs in a meta-analysis by La Distia Nora et al were epiphora, conjunctival injection, and chemosis, which are commonly seen in other forms of viral conjunctivitis [16]. Other reported ocular findings have included both anterior and posterior segment findings such conjunctivitis, uveitis, acute macular neuroretinopathy, and retinopathy [17,18]. Notably, ocular manifestations have occasionally been described as the sole or initial presentation of SARS-CoV-2 infection [19][20][21].…”

Section: Discussionmentioning

confidence: 99%

Ocular symptoms in COVID-19 infection: a survey study

McHarg

Wang

Yakin

et al. 2022

J Ophthal Inflamm Infect

View full text Add to dashboard Cite

Background Coronavirus disease 2019 (COVID-19) systemic symptoms and sequelae have been studied extensively, but less is known about the characterization, duration, and long-term sequelae of ocular symptoms associated with COVID-19 infection. The purpose of this study was to analyze the frequency, spectrum, and duration of ocular symptoms in participants with COVID-19 infection treated in inpatient and outpatient settings. Methods A retrospective electronic survey was distributed to NIH employees and the public who reported testing positive for SARS-CoV-2. The anonymous survey collected information on demographics, past ocular history, systemic COVID-19 symptoms, and ocular symptoms. Results A total of 229 (21.9% male and 78.1% female, mean age 42.5 ± 13.9) survey responses were included. Ocular symptoms were reported by 165 participants with a mean of 2.31 ± 2.42 symptoms. The most commonly reported ocular symptoms were light sensitivity (31.0%), itchy eyes (24.9%), tearing (24.9%), eye redness (24.5%), and eye pain (24.5%). Participants with ocular symptoms had a higher number of systemic symptoms compared to participants without ocular symptoms (mean 9.17 ± 4.19 vs 6.22 ± 3.63; OR: 1.21; 95% CI: 1.11 – 1.32; p < 0.001). Ocular symptoms were more common in those who reported a past ocular history compared to those who did not (81.8% vs 67.1%; OR: 2.17; 95% CI: 1.08 – 4.37; p = 0.03). Additionally, the onset of ocular symptoms occurred most frequently at the same time as systemic symptoms (47.5%), and 21.8% reported symptoms lasting ≥ 14 days. Conclusions Ocular surface-related symptoms are the most frequent ocular manifestations, and systemic disease severity is associated with the presence of ocular symptoms. Additionally, our results show that ocular symptoms can persist post-COVID-19 infection. Further work is needed to better understand ocular symptoms in COVID-19 and long-term sequelae.

show abstract

Section: Discussionmentioning

confidence: 99%

Ocular symptoms in COVID-19 infection: a survey study

McHarg

Wang

Yakin

et al. 2022

J Ophthal Inflamm Infect

View full text Add to dashboard Cite

show abstract

“…4e, f, h, i). [3,6,7,9] und/oder der Choriokapillaris [5] und inneren Choroidea [9]. In unserem Fall zeigte sich ein verminderter Blutfluss in Choriokapillaris und Choroidea.…”

Section: Klinischer Befundunclassified

“…Die Literaturrecherche zeigt zudem, dass im Rahmen von COVID-19 eine AMN gehäuft auch bei älteren Personen zu beobachten ist [4,10]. Bei Sehstörungen im Rahmen von COVID-19 sollte bei älteren Patienten daher nicht nur an die Conjunctivitis sicca, welche die häufigste Beteiligung von COVID-19 am Auge darstellt [3], sondern auch an eine mögliche AMN gedacht werden. Die Symptomabfrage mit dem Amsler-Gitter (der Patient wird gebeten, die wahrgenommenen Skotome auf einem Amsler-Gitter einzuzeichnen) kann bei Immobilität oder unter Isolationsbedingungen hilfreich sein, wenn keine OCT zur Verfügung steht.…”

Section: Diagnostikunclassified

“…Regelmäßige augenärztliche Kontrollen inklusive der OCT dienen dem Ausschluss anderer retinaler COVID-Manifestationen, wie z. B. retinaler Blutungen oder Gefäßverschlüsse [3].…”

Section: Diagnostikunclassified

“…In unserem Fall zeigte sich ein verminderter Blutfluss in Choriokapillaris und Choroidea. In den allermeisten bisher beschriebenen Fallberichten besteht mindestens ein weiterer Risikofaktor, meist eine orale Kontrazeption [3,5]. Da diese in dem hier vorliegenden Fall verneint wurde und keine weiteren Komorbiditäten bekannt waren, ist davon auszugehen, dass eine AMN auch durch COVID-19 allein ausgelöst werden kann.…”

Section: Klinischer Befundunclassified

See 2 more Smart Citations