Acute mania in a patient with hypothyroidism resulting from Hashimoto's Thyroiditis

Lin, Chia-Lin; Yang, Szu‐Nian; Shiah, I‐Shin

doi:10.1016/j.genhosppsych.2013.06.013

Cited by 12 publications

(19 citation statements)

References 3 publications

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“…As a matter of fact, the most common psychiatric symptoms related to hypothyroidism are depression and cognitive dysfunction . Various studies have pointed out that hypothyroidism is also associated with mania . A neurobiological underpinning might therefore be that thyroid hormone receptors are widely distributed in the brain, and that interactions between the thyroid and neurotransmitter systems might explain the effect of thyroid hormones on both depressed and euphoric mood states in individuals with BD .…”

Section: Discussionmentioning

confidence: 99%

Psychiatric and physical comorbidities and their impact on the course of bipolar disorder: A prospective, naturalistic 4‐year follow‐up study

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Psychiatric and physical comorbidities and their impact on the course of bipolar disorder: A prospective, naturalistic 4‐year follow‐up study

et al. 2017

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“…In autoimmune thyroiditis presenting with mood disorders (Table 3 ), thyroid hormone substitution has been used in case of hypothyroidism (Schmidt et al 1990 ; Mahmud et al 2003 ; Stowell and Barnhill 2005 ; Tor et al 2007 ; Liu et al 2011 ; Lin et al 2013 ) or antithyroid drugs in case of hyperthyroidism (Bokhari et al 1998 ; Müssig et al 2005 ).…”

Section: Discussionmentioning

confidence: 99%

“…A different group in Taiwan reported acute mania in a 41-year-old woman with no history of psychiatric illness. Both mania and hypothyroidism (resulting from Hashimoto’s thyroiditis as confirmed by diffusely heterogeneous and hypoechoic pattern in ultrasonography and lymphoid cell infiltration in fine needle aspiration cytology), remitted gradually within 3 weeks after treatment with levothyroxine, valproate, and quetiapine (Lin et al 2013 ).…”

Section: Reviewmentioning

confidence: 99%

Bipolar disorder and antithyroid antibodies: review and case series

Bocchetta

Traccis

Mosca

et al. 2016

Int J Bipolar Disord

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Mood disorders and circulating thyroid antibodies are very prevalent in the population and their concomitant occurrence may be due to chance. However, thyroid antibodies have been repeatedly hypothesized to play a role in specific forms of mood disorders. Potentially related forms include treatment-refractory cases, severe or atypical depression, and depression at specific phases of a woman’s life (early gestation, postpartum depression, perimenopausal). With regard to bipolar disorder, studies of specific subgroups (rapid cycling, mixed, or depressive bipolar) have reported associations with thyroid antibodies. Offspring of bipolar subjects were found more vulnerable to develop thyroid antibodies independently from the vulnerability to develop psychiatric disorders. A twin study suggested thyroid antibodies among possible endophenotypes for bipolar disorder. Severe encephalopathies have been reported in association with Hashimoto’s thyroiditis. Cases with pure psychiatric presentation are being reported, the antithyroid antibodies being probably markers of some other autoimmune disorders affecting the brain. Vasculitis resulting in abnormalities in cortical perfusion is one of the possible mechanisms.

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“…Concomitance of Hashimoto thyroiditis and mania is a rare condition in the literature (25). In our case, symptoms such as increased self-esteem, grandiosity thoughts, increased amount and speed of speech, increased targeted activities, and flying thoughts which we expected during a manic episode were absent, presence of persecution delusions and behavioral disorders related to delusions primarily helped us to rule out mania.…”

Section: Discussionmentioning

confidence: 57%

Psychosis related with Hashimoto thyroiditis: a case report

Ağaçhanlı¹,

Balaban²,

Yazar³

et al. 2016

Dusunen Adam

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Psychosis related with Hashimoto thyroiditis: a case reportHashimoto's thyroiditis is an autoimmune disease characterized with inflammation of the thyroid gland.Psychiatric symptoms frequently accompany Hashimoto's thyroiditis. Major depression is the most common affective disorder with the prevalence of 33-43%. Psychotic disorders may accompany at 5% rate. In this case report; a patient, recently diagnosed with hypothyroidism and involved into a psychotic process due to his hypothyroidism, is discussed. The patient's refusal of oral intake and lack of parenteral preparation of thyroxine in our country were the factors that made the treatment more complicated. The aim of this case report is to emphasize the importance of the routine laboratory examinations especially during the first admission to the hospital, and to underline difficulty of thyroid replacement therapy due to lack of preparation of parenteral thyroxine in our country in patients who do not or can not get medications orally.

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Acute mania in a patient with hypothyroidism resulting from Hashimoto's Thyroiditis

Cited by 12 publications

References 3 publications

Psychiatric and physical comorbidities and their impact on the course of bipolar disorder: A prospective, naturalistic 4‐year follow‐up study

Psychiatric and physical comorbidities and their impact on the course of bipolar disorder: A prospective, naturalistic 4‐year follow‐up study

Bipolar disorder and antithyroid antibodies: review and case series

Psychosis related with Hashimoto thyroiditis: a case report

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