“…In horses and humans, primary respiratory tract infections rarely extend to the mediastinum (Pierce, 2000;Griffin, 2002). Primary mediastinitis is rare in humans (Pierce, 2000). Some cases of Staphylococci-and Streptococci-associated purulent mediastinitis and mediastinal abscesses have been reported in humans and horses primary of unknown origin or secondary to bacteriemia, pleuritis, strangles (Shishido et al, 1997;Griffin, 2002;Chang et al, 2009;Kouritas et al, 2012;Waller et al, 2014).…”