Acute methyl iodide exposure with delayed neuropsychiatric sequelae: Report of a case

Abstract

The findings in the case patient may advance our understanding of the mechanisms and clinical manifestations of chronic neurotoxicity after exposure to methyl iodide.

Fumigant methyl iodide can methylate inorganic mercury species in natural waters

“…With the phase out of CH 3 Br, the use of CH 3 I is expected to increase dramatically in the future. CH 3 I is a pulmonary and dermal irritant 26 , and is also suspected to be carcinogenic 34 , neurotoxic 18,26 and endocrine disrupting 4 . This study shows that CH 3 I could also indirectly threaten the health of humans and wildlife by forming a toxic chemical, CH 3 Hg þ , suggesting the necessity of a more comprehensive risk assessment of CH 3 I use as a fumigant.…”

“…CH 3 I applied to soils can be quickly leached out with concentration reaching 0.20-2.22 mmol l À 1 depending on the soil type used ( Supplementary Fig. 9), which is two to five order of magnitude higher than its concentration in coastal waters 26 . The reaction of Hg 2 þ and CH 3 I in pond water can be described as a pseudosecond-order reaction (Fig.…”

Methyl Iodide Exposure Presenting as Severe Chemical Burn Injury with Neurological Complications and Prolonged Respiratory Insufficiency

“…3 Until now, only 13 documented cases of methyl iodide exposure-induced injury have been reported. [6][7][8][9] These cases, in particular, describe different neurological malfunctions such as vertigo, ataxia, diplopia, agitation, confusion, delirium, episodes of giddiness and sleepiness, nystagmus, strabismus, coma, cerebellar signs, or paresis. 6 In one case, methyl iodide exposure led to death.…”

MRI brain in monohalomethane toxic encephalopathy: A case report

“…[12345] As far as we know, none of them mention abnormal magnetic resonance imaging (MRI) findings except one. [1]…”