a b s t r a c tPrimary cardiac neoplasms are very rare, with an incidence less than 0.2% in unselected patients at autopsy. Of these, cardiac myxomas are the most common benign cardiac tumors in the adult. Atrial myxomas are a rare source of coronary artery embolism. Coronary embolism as the first presentation of cardiac myxoma is extremely uncommon. We report a case of acute inferior wall ST elevation myocardial infarction (STEMI) caused by embolization of the tumor fragment from left atrial myxoma into the left circumflex coronary artery. The patient was successfully treated by percutaneous coronary intervention with catheter aspiration of the embolized tumor fragment followed by surgical excision of the tumor.