Acute Nephritis and Pulmonary Alveolitis Following Pneumococcal Pneumonia

Post‐streptococcal acute glomerulonephritis associated with pneumococcal infection

“…Acute glomerulonephritis associated with pneumococcal infection has certain specific characteristics, as previously reported: the interval between the primary pneumococcal infection and AGN is approximately 24–48 h; reversible hypocomplementemia occurs, as shown by laboratory tests; and renal failure is commonly mild, transient and reversible, although a few patients have required a short period of dialysis . Although the present clinical course was consistent with previous reports on pneumococcal AGN, it is improbable that pneumococcal infection was responsible for the increase in ASO titers.…”

“…We report here a pediatric patient with febrile post‐streptococcal acute glomerulonephritis (PSAGN) associated with pneumococcal bacteremia. Interestingly, the present clinical course was consistent with those of prior reported cases of AGN associated with pneumococcal infection . To our knowledge, there have been few reports on the relationship between pneumococcal infection and the incidence of PSAGN.…”

“…Group A β‐hemolytic Streptococcus (GAS), specifically Streptococcus pyogenes , is the most common cause of post‐infectious glomerulonephritis. Although other infectious causes are less common, several cases of acute glomerulonephritis (AGN) following infection with S. pneumoniae have been reported . We report here a pediatric patient with febrile post‐streptococcal acute glomerulonephritis (PSAGN) associated with pneumococcal bacteremia.…”

Pneumococcal meningitis associated with glomerulonephritis: A case report

“…Unfortunately, we were unable to test for serotype of the pneumococcus. So far pneumococcus types 5, 6C, 7, 9, 14, 15 and 17F have been isolated from patients who developed a glomerulonephritis following a pneumococcal infection, and those serotypes have been suggested to be nephritogenic strains 40,[44][45][46][47][48] . Although, in one of these patients, a 4-year-old girl described by Hyman et al 48 , type 14 pneumococcal antigen was detected in the kidney 48 implying that the pneumococcal antigens may play a role in the local activation of the immune response, we could not find any evidence supporting significance of particular serotypes in the development of nephritis from the available literature.…”

Post-Infectious Glomerulonephritis

“…A number of infections can cause nephritis as listed in table 1. Most have been reported as case reports, such as a report of nephritis following malaria due to falciparum vivax infection in a 7 year old girl [23], and a report of nephritis following pneumococcal pneumonia in an adult male [24]. Hepatitis-B-associated glomerulonephritis (HBGN) is a distinct entity occurring frequently in hepatitis-B-prevalent areas of the world.…”