Acute nutmeg intoxication

Abernethy, Michael; Becker, Lance B.

doi:10.1016/0735-6757(92)90069-a

Cited by 43 publications

(14 citation statements)

References 5 publications

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“…Case reports exist of anticholinergic intoxication from moonflower seeds (Datura inoxia) (DeFrates et al 2005), nutmeg (Abernethy and Becker 1992), and angels trumpet (Brugmansia) (Isbister et al 2003;Gopel et al 2002).…”

Section: Drug Definitionmentioning

confidence: 98%

Neuropsychiatric Effects of Prescription Drug Abuse

et al. 2007

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Prescription drugs have become a major category of abused substances, and there is evidence that the prevalence of prescription drug abuse may soon overtake that of illicit drugs. Study of prescription drugs has been hampered by vague terminology, since prescription drugs are only separated from other drugs of abuse by social and legal constructs. Reviewed herein is published literature on the abuse of four major categories of abused prescription drugs: sedative-hypnotics, stimulants, anabolic steroids, and anticholinergics. The review emphasizes evidence regarding the effects of these drugs on neural systems. Other abused prescription drugs that fall outside of the major categories are also briefly addressed.

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Section: Drug Definitionmentioning

confidence: 98%

Neuropsychiatric Effects of Prescription Drug Abuse

et al. 2007

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“…The unusual symptoms and signs settled with conservative management. In the symptomatology of our patient with nutmeg poisoning, urine retention, dry mouth, palpitations and mydriasis were observed, which are similar in some aspects to anti-cholinergic or atropine poisoning [5]. This should be considered by emergency and intensive medicine physicians.…”

Section: Resultsmentioning

confidence: 93%

“…Myristicin also has weak monoamine oxidase inhibiting properties, which may be responsible for some of its cardiovascular effects [3]. Both myristicin and elemicin have anti-cholinergic and psychotropic properties, the effects of which were clearly seen in our patient [5].…”

Section: Discussionmentioning

confidence: 91%

Acute nutmeg poisoning

McKenna

Nordt²,

Ryan³

2004

European Journal of Emergency Medicine

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We present a case of acute nutmeg poisoning in a 16-year-old youth who had ingested the substance for recreational purposes. He developed a number of neurological symptoms and signs along with non-specific electrocardiographic changes and anti-cholinergic-type symptoms. We describe the pharmacology of nutmeg and its constituents, discuss its metabolism, and make recommendations about the management of nutmeg poisoning. Emergency staff should be aware of the effects of nutmeg, which may present in marijuana users who seek alternative substances.

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“…13 The ingestion of 25 -28 g of nutmeg powder produced tachycardia, anxiety, miosis, paresthesias, palpitations, anticholinergic signs (mydriasis, difficulty voiding, tachycardia), and paranoid behavior without hallucinations. 14,15 The ingestion of an estimated dose of 37 g nutmeg blended in a milkshake was associated with tachycardia, palpitations, drowsiness, nausea, dry mouth, anxiety, restlessness, and agitation without hallucinations. 16 Variation in toxicity may result from the loss of essential oils from the ground nutmeg.…”

Section: Dose Responsementioning

confidence: 99%

Nutmeg (Myristica fragransHoutt.)

2008

Medical Toxicology of Natural Substances

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Acute nutmeg intoxication

Cited by 43 publications

References 5 publications

Neuropsychiatric Effects of Prescription Drug Abuse

Neuropsychiatric Effects of Prescription Drug Abuse

Acute nutmeg poisoning

Nutmeg (Myristica fragransHoutt.)

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