Acute Obstructive Cholangitis A Distinct Clinical Syndrome

Reynolds, Benedict M.; Dargan, Everett L.

doi:10.1097/00000658-195908000-00013

Cited by 177 publications

(73 citation statements)

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“…Die klassisches Charcot'sche Trias -Fieber, Gelbsucht und rechtsseitige Oberbauchschmerzen -liegt jedoch bei weniger als 60% der Patienten vor [25]. Die Symptomatik kann von einer leichten Ausprägung ohne alle klassischen Charakteristika [26] bis zum septischen Schock reichen [27]. Laborchemisch findet sich neben den Zeichen der Cholestase und Entzündungsparametern bei etwa einem Drittel der Patienten eine Erhöhung des Amylasewerts.…”

Section: Akute Gallensteinbedingte Cholangitisunclassified

Cholelithiasis

Heller¹,

Sauerbruch²

2002

Visc Med

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The incidence of complications in patients with symptomatic gallstone disease is about 1% per year. The most frequent complication is acute cholecystitis. Less frequent complications are acute cholangitis, biliary pancreatitis, Mirizzi syndrome and gallstone ileus. This article reviews the current knowledge of the diagnosis and therapy of these complications including the recommendations of consensus conferences.

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Section: Akute Gallensteinbedingte Cholangitisunclassified

Cholelithiasis

Heller¹,

Sauerbruch²

2002

Visc Med

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“…The classic presentation of cholangitis is Charcot's triad with right upper quadrant pain, fever, and jaundice which occurs in the majority of the patients. However, 10-15% of the patients present with shock or mental confusion which has been termed Reynold's pentad and has a very poor prognosis [82]. Emergency surgery is associated with an overall mortality of 15-30%.…”

Section: Cholangitismentioning

confidence: 99%

Antimicrobial Treatment of Intra-Abdominal Infections

Elsakr

Johnson²,

Younes

et al. 1998

Dig Dis

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There have been several recent changes that influence the management of intra-abdominal infections. These changes include important developments in antibiotic resistance such as increases in pneumococcal resistance, emergence of multi-drug-resistant enterococcal isolates, and decreasing sensitivity of anaerobes and gram-negative rods. In addition there are new antibiotics such as piperacillin/tazobactam, and new antibiotic dosing regimens such as single daily dosing of aminoglycosides. In this article, we will review the therapeutic approach to intra-abdominal infections with special emphasis on the various forms of peritonitis, cholecystitis, cholangitis, and diverticulitis. Several new concepts about the treatment of enterococcus, the management of bacterial and fungal peritonitis, and the prevention of spontaneous bacterial peritonitis will also be reviewed. Specific recommendations for the management of the different infections including antibiotic doses and costs will be provided. Finally the role of invasive procedures in the management of some of the infections will be explored.

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“…About 50-70% of the patients with acute cholangitis present with Charcot's triad [9]. Later, in 1959, Reynolds and Dragan described a syndrome consisting of fever, jaundice, abdominal pain, mental confusion or lethargy and shock [10]. They called it Reynold's pentad with the underlying pathology of acute obstructive cholangitis.…”

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confidence: 99%

Management of acute cholecystitis and acute cholangitis in emergency setting

2014

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AbstractAcute biliary infection (acute cholecystitis and acute cholangitis) is one of the common emergency conditions which carries significant morbidity and mortality. The risk factors are often associated with gallstones, biliary stasis and bile infection. Gram-negative bacteria are frequent isolates from bile and blood cultures in infectious cholangitis. Endotoxaemia from the gram-negative microbes results in circulatory shock and organ dysfunction. Therefore, prompt diagnosis with severity stratification and recognition of its potential rapid progression to life-threatening shock and multi-organ failure ensure execution of the three fundamental interventions in the initial management strategy, namely: resuscitation to support the organ, antimicrobial therapy and biliary decompression drainage to control the infection. This is the core principle in the management of severe acute cholangitis.

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Acute Obstructive Cholangitis A Distinct Clinical Syndrome

Cited by 177 publications

References 0 publications

Cholelithiasis

Cholelithiasis

Antimicrobial Treatment of Intra-Abdominal Infections

Management of acute cholecystitis and acute cholangitis in emergency setting

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