Acute otitis media in infants less than three months of age: Clinical presentation, etiology and concomitant diseases

Sakran, Waheeb; Makary, Hassan; Colodner, Raul; Ashkenazi, Dror; Rakover, Yoseph; Halevy, Raphaël; Koren, Ariel

doi:10.1016/j.ijporl.2005.08.003

Cited by 22 publications

(32 citation statements)

References 22 publications

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“…As in previous reports, we have also observed both the predominance of S pneumoniae and H influenzae , and the rarity of Moraxella as causative pathogens of AOM in the first 2 months of life 6 – 11. It is of note that pneumococcal vaccine has not been included in routine immunisation programme in Israel.…”

Section: Discussionsupporting

confidence: 88%

“…Early onset AOM predicts later recurrent or chronic otitis media and impaired hearing 5. Although infectious diseases in early infancy are common and responsible for substantial mortality and morbidity, there are relatively few studies of ear infections at this very young age 6 – 11. Several trends in AOM characteristics have been recently reported including a change in its prevalence and in the profile of pathogenic bacteria 12 – 15.…”

mentioning

confidence: 99%

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Acute otitis media in the first two months of life: characteristics and diagnostic difficulties

Berkun

Nir-Paz

Ami

et al. 2008

Archives of Disease in Childhood

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The absence of predictors for bacterial infection in more than 70% of bacterial AOM suggests that empirical antibiotic treatment should be advised for the young infants with AOM even when afebrile and with normal laboratory profile. A low diagnostic rate of AOM by the paediatrician emphasizes the need for improvement in examination skills and instrumentation to allow a thorough ear evaluation in children of a very young age.

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Section: Discussionsupporting

confidence: 88%

mentioning

confidence: 99%

Acute otitis media in the first two months of life: characteristics and diagnostic difficulties

Berkun

Nir-Paz

Ami

et al. 2008

Archives of Disease in Childhood

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“…Ladomenou et al, 2010;Sakran et al, 2006). At the CUH the mean age of the patients was 23.97 years, with 1.5% under one year old, and 33.7% between 1 and 12 years.…”

Section: Discussionmentioning

confidence: 96%

Differentiating between rhinosinusitis and mastoiditis surgery from postmortem medical training: A study of two identified skulls and hospital records from early 20th century Coimbra, Portugal

Magalhães

Lopes

Santos

2017

International Journal of Paleopathology

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Differentiating between medical procedures performed antemortem, perimortem or postmortem in skeletal remains can be a major challenge. This work aims to present evidence of procedures to treat rhinosinusitis (RS) and mastoiditis, suggest criteria for the diagnosis of frontal sinus disease, and frame the individuals described in their medical historical context. In the International Exchange collection, the skull (878) of a 24-year-old male, who died in 1933 due to frontal sinusitis and meningitis, presents evidence of a trepanation above the right frontonasal suture, and micro/macroporosity on the superciliary arches. The available Coimbra University Hospitals archives reported that 46 females and 59 males (aged 15 months-84 y.o., x− = 35.33) underwent surgery to treat RS, primarily by trepanation (94.3%). In a search for similar evidence in the collection, the skull of a 42-year-old female (85), who died in 1927 due to sarcoma in the abdomen, shows four quadrangular holes located above the right supraorbital notch, right and left maxilla, and left mastoid process. The number/location of the holes and cut marks point to postmortem medical training (possible dissection). This paper discusses the value of information from historical contexts to differentiate between surgery and medical training in the paleopathological record.

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“…This predominance of UTI as the cause of CSI is well-recognized in young febrile infants with OM and infants with fever of unknown origin; however, it has not been reported with other FBIs in this age group. 1,5,9,11,19,33 Specifically, there has not been a reported relationship between UTI and skin or soft tissue infections. However, 2 of our 4 infants with a CSI had a UTI in addition to their skin or soft tissue infection: the 32-dayold male with a buttock abscess and E. coli UTI; and the 21-day-old female with truncal cellulitis and E. coli UTI.…”

Section: Utimentioning

confidence: 99%

Evaluation, management, and outcome of focal bacterial infections (FBIs) in nontoxic infants under two months of age

Vidwan

Geis

2010

Journal of Hospital Medicine

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BACKGROUND:Well‐appearing young infants with focal bacterial infections present to the emergency department (ED) and are often admitted for a sepsis evaluation of blood, urine, and spinal fluid. However, the risk of concomitant systemic infections (CSI) in this population is not well reported, specifically comparing febrile to afebrile infants. We hypothesized that afebrile, well‐appearing infants under two months of age with a defined focal bacterial infection on exam have a very low risk of CSI.METHODS:This retrospective study was conducted at an urban, academic, tertiary care pediatric hospital ED on patients seen from January 2000‐December 2005. Eligible infants were less than 60 days of age, well‐appearing on exam, and with normal‐for‐age vital signs who presented with a focal bacterial infection on exam. Exclusion criteria included immunodeficiency, indwelling catheter, previous admission for bacterial infection, or current use of systemic antibiotics. Main study outcome was risk of CSI in febrile and afebrile groups.RESULTS:One hundred ninety seven patients were included in the study population. Of these, 39 were febrile and 158 were afebrile. Four patients had a documented CSI: one case of S. pneumoniae bacteremia and three cases of E. coli urinary tract infection. Of these 4 infants, 3 were febrile (7.7% CSI risk) and 1 was afebrile (0.6%). Febrile infants had a significantly higher risk of CSI (OR 13.1, 95% CI 1.3, 129.5).CONCLUSIONS:CSI is very uncommon in afebrile, well‐appearing infants under 60 days of age with a focal bacterial infection. Journal of Hospital Medicine 2010;5:76–82. © 2010 Society of Hospital Medicine.

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Acute otitis media in infants less than three months of age: Clinical presentation, etiology and concomitant diseases

Cited by 22 publications

References 22 publications

Acute otitis media in the first two months of life: characteristics and diagnostic difficulties

Acute otitis media in the first two months of life: characteristics and diagnostic difficulties

Differentiating between rhinosinusitis and mastoiditis surgery from postmortem medical training: A study of two identified skulls and hospital records from early 20th century Coimbra, Portugal

Evaluation, management, and outcome of focal bacterial infections (FBIs) in nontoxic infants under two months of age

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