Acute Oxalate Nephropathy Caused by Excessive Vegetable Juicing and Concomitant Volume Depletion

Chaudhari, Harshad; Michaud, Jennine; Srialluri, Nityasree; Mahendrakar, Smita; Granz, Christine; Yudd, Michael

doi:10.1155/2022/4349673

Cited by 6 publications

(6 citation statements)

References 16 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dennoch wird oftmals in Off-Label-Use Icodextrin insbesondere bei Patienten mit einem hohen Ultrafiltrationsverlust oder bei Patienten, bei denen die Einsparung von Glukose unerlässlich ist, mit mehr als einem täglichen Wechsel eingesetzt 31 – 33 . Derzeit wird eine große multizentrische Studie (DIDo) zur Wirksamkeit und Sicherheit des Einsatzes 2-maliger Icodextrin-Applikation pro Tag bei älteren PD-Patienten durchgeführt.…”

Section: Maßnahmen Und Therapieansätze Zum Langzeiterhaltunclassified

Maßnahmen zum peritonealen Langzeiterhalt

Oberacker,

Schanz,

Latus

et al. 2024

Nephrologie aktuell

View full text Add to dashboard Cite

ZUSAMMENFASSUNGDie Zahl an Patienten, die auf ein Nierenersatzverfahren angewiesen sind, steigt stetig. Die Peritonealdialyse (PD) ist eine Methode zur Nierenersatztherapie, die hinsichtlich der Lebensqualität und Patientenautonomie häufig Vorteile gegenüber der Hämodialyse bieten kann. Allerdings ist die Langzeit-PD mit chronischen Veränderungen der Peritonealmembran wie Fibrose assoziiert, die den Teilchen- und Wassertransport erheblich beeinträchtigen und zum Ultrafiltrationsversagen führen können. Schlimmstenfalls treten schwere Komplikationen wie die enkapsulierende Peritonealsklerose (EPS) auf. In einigen Fällen kommt es sehr früh, d. h. nach etwa 5 Jahren oder weniger, zu Veränderungen, die zu einem Therapieversagen führen, sodass die PD beendet werden muss. Daher ist der möglichst lange Funktionserhalt der Membran von großer Bedeutung. In diesem Beitrag geben wir einen Überblick über Maßnahmen zum peritonealen Langzeiterhalt sowie einen Ausblick auf neue, potenzielle Therapeutika, die zu einer längeren Integrität der Peritonealmembran beitragen könnten.

show abstract

Section: Maßnahmen Und Therapieansätze Zum Langzeiterhaltunclassified

Maßnahmen zum peritonealen Langzeiterhalt

Oberacker,

Schanz,

Latus

et al. 2024

Nephrologie aktuell

View full text Add to dashboard Cite

show abstract

“…Proximal Tubular Damage, 38.7 kDa (34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44), transmembrane glycoprotein type-1, also activated in also response to ischemic and toxic kidney damage [29,[31][32][33]. Expressed in: proximal tubular cells, microglial cells, excitatory neurons, oligodendrocytes, and inhibitory neurons [31,32].…”

Section: Analytementioning

confidence: 99%

Potential Biomarkers for the Earlier Diagnosis of Kidney and Liver Damage in Acute Intermittent Porphyria

Storjord,

Wahlin,

Karlsen

et al. 2023

Life

View full text Add to dashboard Cite

Acute intermittent porphyria (AIP) is an inherited metabolic disorder associated with complications including kidney failure and hepatocellular carcinoma, probably caused by elevations in the porphyrin precursors porphobilinogen (PBG) and delta-aminolevulinic acid (ALA). This study explored differences in modern biomarkers for renal and hepatic damage between AIP patients and controls. Urine PBG testing, kidney injury panels, and liver injury panels, including both routine and modern biomarkers, were performed on plasma and urine samples from AIP cases and matched controls (50 and 48 matched pairs, respectively). Regarding the participants’ plasma, the AIP cases had elevated kidney injury marker-1 (KIM-1, p = 0.0002), fatty acid-binding protein-1 (FABP-1, p = 0.04), and α-glutathione S-transferase (α-GST, p = 0.001) compared to the matched controls. The AIP cases with high PBG had increased FABP-1 levels in their plasma and urine compared to those with low PBG. In the AIP cases, KIM-1 correlated positively with PBG, CXCL10, CCL2, and TCC, and the liver marker α-GST correlated positively with IL-13, CCL2, and CCL4 (all p < 0.05). In conclusion, KIM-1, FABP-1, and α-GST could represent potential early indicators of renal and hepatic damage in AIP, demonstrating associations with porphyrin precursors and inflammatory markers.

show abstract

“…The role of LPD/VLPD/sLPD in this setting is not well studied. Note that several vegetables are high in oxalate meaning that the traditional LPD/VLPD/ SLPD may not be the optimal dietary tool chosen for those with oxalate nephropathy proven on biopsy or heavily suspected based on clinical grounds [26,27].…”

Section: Oxalate Nephropathymentioning

confidence: 99%

New and old approaches to nutritional management of acute and chronic glomerulonephritis

Hanna

Ahdoot

Rhee

et al. 2022

Current Opinion in Nephrology &Amp; Hypertension

View full text Add to dashboard Cite

Purpose of review It has been well published that a low protein diet (0.6–0.8 g/kg/day) is optimal for nutritional management of chronic kidney disease and with care be used without inducing protein malnutrition. Recent findings Though care with this approach must be demonstrated in patients with end-stage renal disease and with prominent protein energy wasting, another category of renal patient exists for whom dietary recommendations need more exploration. The Kidney Disease Improving Global Outcomes consortium, actually identifies renal disease as those patients with reduced filtration and those with excessive proteinuria excretion. Proteinuria, indeed, has proven to be a serious marker predisposing renal patients to atherosclerotic heart disease, venous thromboembolism, cerebrovascular accidents, and overall mortality. We discuss what is known about nutritional strategies to curb proteinuria and control inflammation in the setting of glomerulonephritis. Summary While this area of management of a set of conditions maybe nascent, it has the potential to provide incredible breakthroughs in nutritional management of auto immune diseases of the kidney specifically and the body writ large.

show abstract

Acute Oxalate Nephropathy Caused by Excessive Vegetable Juicing and Concomitant Volume Depletion

Cited by 6 publications

References 16 publications

Maßnahmen zum peritonealen Langzeiterhalt

Maßnahmen zum peritonealen Langzeiterhalt

Potential Biomarkers for the Earlier Diagnosis of Kidney and Liver Damage in Acute Intermittent Porphyria

New and old approaches to nutritional management of acute and chronic glomerulonephritis

Contact Info

Product

Resources

About