Acute Pancreatitis after Embolization of Liver Tumors: Frequency and Associated Risk Factors

López-Benítez, Rubén; Radeleff, Boris; Barragán-Campos, Héctor Manuel; Noeldge, Gerd; Grenacher, Lars; Richter, G. M.; Sauer, Peter; Büchler, Markus W.; Kauffmann, G. W.; Hallscheidt, Peter

doi:10.1159/000101878

Cited by 37 publications

(23 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Chemoembolization also has infrequent but significant complications such as tumor rupture and pancreatitis. 29,30 Therefore, the combination of nominal toxicity, expanded efficacy, and noninvasiveness without some of the technical and anatomic contraindications of other modalities warrants continued investigation into SBRT for liver malignancies. Clinical outcomes are already being reported anecdotally and can be appreciated by the following 2 cases treated at our institution.…”

Section: Discussionmentioning

confidence: 99%

Stereotactic Body Radiation Therapy for Liver Metastases and Primary Hepatocellular Carcinoma: Normal Tissue Tolerances and Toxicity

2010

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Stereotactic Body Radiation Therapy for Liver Metastases and Primary Hepatocellular Carcinoma: Normal Tissue Tolerances and Toxicity

2010

View full text Add to dashboard Cite

“…Lethal outcome from this complication is generally low (1-2%) but can be as high as 30-50% when sepsis and multiorgan failure develop [18,19].…”

Section: Discussionmentioning

confidence: 99%

Fatal ischemic acute pancreatitis complicating trans-catheter arterial embolization of small hepatocellular carcinoma: Do the risks outweigh the benefits?

Addario

Costanzo

Tritto

et al. 2008

Journal of Hepatology

View full text Add to dashboard Cite

Hepatocellular carcinoma (HCC) is an accepted indication for liver transplantation (LT). Pre-LT adjuvant ablation treatments to prevent tumour progression and drop out from the waiting list have been increasingly adopted at most transplant centers. Trans-catheter arterial chemo-embolization (TACE) is frequently used, but the procedure can be difficult and severe complications may arise. Among them, acute ischemic pancreatitis occasionally occurs and may clinically mimic a post-embolization syndrome. Fatal outcomes of this complication have been reported exceptionally but never in patients awaiting LT. The present case raises concern about the widespread application of TACE and highlights the need for a critical evaluation of the risks and benefits to patients with monofocal small HCC who are scheduled for LT. Superselective embolization of the tumour-feeding artery and systematic monitoring of serum pancreatic enzymes after this radiological procedure are recommended.

show abstract

“…The rest of the pancreas, which is richly supplied by branches of SMA, is rarely the primary site of injury (4). The incidence of acute pancreatitis following TACE ranges from 1.7% to 15.2% (4,5). Acute pancreatitis can develop within 24 hours to up to 15 days after TACE procedure (6,7).…”

Section: Discussionmentioning

confidence: 99%

Acute pancreatitis as a complication of trans-arterial chemoembolization of hepatocellular cancer—case report and review of literature

Krishnamurthy

Brown

Agrawal

et al. 2017

J. Gastrointest. Oncol.

View full text Add to dashboard Cite

Transarterial chemoembolization (TACE) is a therapeutic procedure often performed for hepatocellular carcinoma (HCC). Local complications, though generally uncommon, can arise from arterial ischemia and local cytotoxicity from the chemotherapeutic delivery. We present a case of acute pancreatitis as a rare complication of the TACE procedure along with a review of literature of this uncommon adverse effect.

show abstract

Acute Pancreatitis after Embolization of Liver Tumors: Frequency and Associated Risk Factors

Cited by 37 publications

References 31 publications

Stereotactic Body Radiation Therapy for Liver Metastases and Primary Hepatocellular Carcinoma: Normal Tissue Tolerances and Toxicity

Stereotactic Body Radiation Therapy for Liver Metastases and Primary Hepatocellular Carcinoma: Normal Tissue Tolerances and Toxicity

Fatal ischemic acute pancreatitis complicating trans-catheter arterial embolization of small hepatocellular carcinoma: Do the risks outweigh the benefits?

Acute pancreatitis as a complication of trans-arterial chemoembolization of hepatocellular cancer—case report and review of literature

Contact Info

Product

Resources

About