Acute pancreatitis associated with biliary disease in children

Choi, Bo Hwa; Lim, Yeon Jung; Yoon, Chong Hyun; Kim, Ellen Ai-Ran; Kim, Kyung Mo

doi:10.1046/j.1440-1746.2003.03080.x

Cited by 38 publications

(46 citation statements)

References 28 publications

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“…The results of this pediatric sample show that pancreatitis can have multiple and complex etiologies in children. Among the diverse range of etiologies of pediatric AP, gallstones and biliary disease seem to play a greater role than previously thought [1,2,10,11,[19][20][21]. In this report, it was also the most common (24.3%) etiological cause.…”

Section: Resultsmentioning

confidence: 45%

Acute pancreatitis in children: a tertiary hospital report

Antunes

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Mesquita

et al. 2014

Scandinavian Journal of Gastroenterology

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Introduction. The incidence of acute pancreatitis (AP) in children has increased significantly in the past two decades. Objective. All cases of AP, acute recurrent pancreatitis (ARP), and chronic pancreatitis examined between May 2002 and May 2012 at Hospital de Braga, Portugal, were reviewed. Material and methods. Patients were identified by searching the hospital's electronic discharge records for the International Classification of Disease, Ninth Revision (ICD-9) code 577.0 (acute pancreatitis). ARP was considered as two or more episodes of AP per year or more than three episodes over a lifetime with intervening return to baseline. The following data were analyzed: demographic information, clinical, laboratory and imaging test results, etiology of pancreatitis, medical and surgical management, length of hospitalization, and outcome. The clinical and laboratory factors used in the pediatric acute pancreatitis severity score system and computed tomography severity index (CTSI) score were compared between patients with mild and severe disease. Results. A total of 37 patients, 31 episodes of AP and 6 patients with ARP, were documented. The most prevalent etiologies were biliary stones/sludge (24.3%) and trauma (16.2%). Admission elevated white blood cell count (p = 0.011), 48-h trough calcium (p = 0.007), and 48-h rise in blood urea nitrogen (p = 0.025) correlated significantly with disease severity. CTSI on admission had a score below 4 in three patients with severe disease. Conclusion. This Portuguese pediatric pancreatitis report highlights the multiple and complex etiology of this disease. Better pediatric scoring systems and management algorithms are needed.

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Section: Resultsmentioning

confidence: 45%

Acute pancreatitis in children: a tertiary hospital report

Antunes

Nascimento

Mesquita

et al. 2014

Scandinavian Journal of Gastroenterology

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“…In 10% of cases, gallstones are the underlying cause in newborns and infants. Gallstones or other biliary disorders should be investigated particularly if the patient has jaundice and/or elevated transaminase levels and/or hyperbilirubinemia 12,17,[20][21][22] . Pancreatobiliary anatomical anomalies increase the risk of pancreatitis.…”

Section: (Grade 2/c Full Agreement)mentioning

confidence: 99%

EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis

et al. 2018

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“…Children with choledochal cyst are prone to develop pancreatitis, many due to anomalous pancreatobiliary junction [25,26] . The only case of choledochal cyst in this study had normal amylase and lipase levels.…”

Section: Discussionmentioning

confidence: 99%