Acute pancreatitis following renal allotransplantation

Taft, Peter M.; Jones, Amy C.; Collins, Geoffrey M.; Halasz, Nicholas A.

doi:10.1007/bf01072698

Cited by 25 publications

(8 citation statements)

References 23 publications

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“…In our 5th patient pancreatitis may have been secondary to cytomegalovirus infection and not bil iary calculi. In our patients the incidence of biliary calculi is higher than in previous reports [3,9]; however, the average age of these 3 patients is 55 years, which is greater than most cases reported. As the maximum age of pa tients undergoing renal transplantation has steadily been rising, an increasing incidence of biliary calculi will be encountered.…”

Section: Discussioncontrasting

confidence: 54%

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Acute Pancreatitis following Renal Transplantation

Salem¹,

Williams²,

Blumgart³

1985

Dig Surg

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Acute pancreatitis occurred in 7 patients 3 days to 8 years after renal transplantation. Three patients had or developed biliary calculi which may have been responsible for the disease and 3 patients had cytomegalovirus infections with rising antibody titres. Two patients had more than 1 attack, 1 patient died and 1 patient, during an episode of acute pancreatitis, suffered rejection of the renal allograft which had to be removed. Aetiology, management and the place of surgery are discussed with reference to 1 patient, in whom interventional radiology successfully avoided the need for further surgery.

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Section: Discussioncontrasting

confidence: 54%

“…It occurs in ap proximately 2% of renal transplants at any time from the immediate postoperative period to many years later [1], The mortality is high and is generally reported at over 60% [2,3]. Various aetiologies have been suggested although a specific cause has not been identified.…”

Section: Introductionmentioning

confidence: 99%

Acute Pancreatitis following Renal Transplantation

Salem¹,

Williams²,

Blumgart³

1985

Dig Surg

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“…Pancreatitis following renal transplantation is reported to occur in 0.4 YO-7.0 YO of all cases and to have a mortality of 20% [8,38]. Etiological factors suggested include immunosuppressive medications, viral infections, postoperative hyperparathyroidism, and vasculitis [12,28, 29,351. In our group, the use of azathioprine and prednisolone may have predisposed patients to pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal surgical emergencies following kidney transplantation

Bardaxoglou¹,

Maddern

Ruso

et al. 1993

Transplant Int

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This study reports major gastrointestinal complications in a group of 416 patients following kidney transplantation. Three hundred and ninety-nine patients received a cadaveric kidney while the other 17 received a living related organ. The immunosuppressive regimen changed somewhat during the course of the study but included azathioprine, prednisolone, antilymphocyte globulin, and cyclosporin. Perforations occurred in the colon (n = 6), small bowel (n = 4), duodenum (n = 2), stomach (n = 1), and esophagus (n = 1). There were five cases of acute pancreatitis, four of upper gastrointestinal and two of lower intestinal hemorrhage, two of acute appendicitis, one of acute cholecystitis, one postoperative mesenteric infarction, and two small bowel obstructions. Fifty percent of the complications occurred while patients were being given high-dose immunosuppression to manage either the early postoperative period or episodes of acute rejection. Ten percent of the complications had an iatrogenic cause. Of the 31 patients affected, 10 (30%) died as a direct result of their gastrointestinal complication. This high mortality appears to be related to the effects of the immunosuppression and the associated response to sepsis. Reduction of these complications can be achieved by improved surgical management, preventive measures, prompt diagnosis, and a reduced immunosuppressive protocol.

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“…Acute pancreatitis, after renal transplantation, was first described by Starzl in 1964 (7). The reported incidence has ranged from 1.2% to 6.8%, a rate much higher than that observed in the general population, and with a mortality rate of 10-60% (1,(7)(8)(9).…”

Section: Discussionmentioning

confidence: 93%

Recurrent pancreatitis after renal transplantation in a child

Cho

Hong

Lee

et al. 2008

Pediatric Transplantation

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A five-yr-old girl, who was a renal transplant recipient, presented with nausea, vomiting, epigastric discomfort, papules, and vesicles on her body. She was diagnosed with acute pancreatitis and varicella zoster infection because her serum amylase and lipase levels were positive. Fourteen months later, she was readmitted with nausea, vomiting, and epigastric pain similar to the previous symptoms and was diagnosed with acute pancreatitis. This case report indicates that acute pancreatitis can be one of a number of complications following pediatric renal transplantation and can recur because of various causes.

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Acute pancreatitis following renal allotransplantation

Cited by 25 publications

References 23 publications

Acute Pancreatitis following Renal Transplantation

Acute Pancreatitis following Renal Transplantation

Gastrointestinal surgical emergencies following kidney transplantation

Recurrent pancreatitis after renal transplantation in a child

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