Acute Pancreatitis

Algül, Hana; Weber, Andreas; and, Wolfgang Huber; Schmid, Roland M.

doi:10.1002/9781118512074.ch82

Cited by 4 publications

(3 citation statements)

References 208 publications

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“…Although not described commonly within the liver, peripancreatic necrosis and hemorrhage are seen in necrotizing pancreatitis [ 7 ]. However, in our case, the hepatic bleed manifested almost three weeks after the diagnosis of acute pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Hepatic Hemorrhage: An Unexpected Complication From Enoxaparin

Jog¹,

Rajan²,

Ishak³

et al. 2023

Cureus

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Spontaneous hepatic hemorrhage (SHH) is a rare condition that occurs due to a breach in the liver parenchyma in the absence of an external cause, most commonly from hepatocellular cancer. If a solid liver lesion is absent, then it has been linked with diffuse hepatic diseases or systemic diseases. Although SHH has been linked with the use of warfarin, it has not been thus far linked with enoxaparin. SHH can present with non-specific symptoms, and lab parameters can reveal substantial drops in hemoglobin. It is diagnosed most commonly with computed tomography (CT) imaging and conservative treatment is effective in the majority of cases. We present one such rare case of SHH.

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Section: Discussionmentioning

confidence: 99%

Spontaneous Hepatic Hemorrhage: An Unexpected Complication From Enoxaparin

Jog¹,

Rajan²,

Ishak³

et al. 2023

Cureus

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“…Hz. Peygamber hicretten önce mi yoksa sonra mı olduğu net olarak belli olmayan (Algül, 2005: XXX, 308), Muhâcirler arasında gerçekleştirdiği kardeşleştirmede Hz. Zeyd ile Hz.…”

unclassified

“…Zeyd ile Hz. Hamza'yı kardeş ilan etmişti (İbn Saʻd, 2012: III, 32;Belâzürî, 1996: I, 472;İbnü'l-Esîr, 2009: II, 238;İbn Hacer el-Askalânî, 2001: II, 243;Çağatay, 1997-A: XIII, 547;Erul, 2013: XLIV, 319;Algül, 2005: XXX, 308). Hz.…”

unclassified

Kur Ân Da İsmi̇ Zi̇kredi̇len Tek Sahâbî Zeyd B. Hâri̇se Ni̇n Hayati, Şahsi̇yeti̇ Ve İslâm a Hi̇zmetleri̇

Erkocaaslan¹

2018

jisr

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Changes in pathogen spectrum and antimicrobial resistance development in the time‐course of acute necrotizing pancreatitis

Würstle

Hapfelmeier²,

Wöhrle

et al. 2019

J of Gastro and Hepatol

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Background and AimIn contrast to the first peak of multi‐organ failure in acute pancreatitis, the second peak is mostly triggered by septic complications. Our aim was to analyze the spectrum of pathogens and antimicrobial resistance development in relation to the time‐course of the disease and its clinical outcome.MethodsOne hundred twenty‐two patients with acute necrotizing pancreatitis undergoing pancreas puncture at two tertiary academic medical centers in Germany were retrospectively analyzed.ResultsAt species level, there was a change in spectrum from Enterococcus faecalis (∆d150 − d1 = 14.6% − 16.7% = −2.1%) to Enterococcus faecium (∆d150 − d1 = 93.1% − 16.3% = 76.8%) (P < 0.001) and from Candida albicans (∆d150 − d1 = 39.7% − 23.6% = 16.1%) to non‐albicans Candida spp. (∆d150 − d1 = 43.5% − 6.4% = 37.1%) (P = 0.005). Time‐to‐event analysis of acquired antimicrobial resistance showed that the overall number of patients with Enterobacteriaceae presented an antimicrobial susceptibility decrease by 59.7% (∆d1 − d100 = 87.0% − 27.3% = 59.7%). The cumulative incidence of multi‐resistant bacteria increased with length of hospital stay (∆d150 − d1 = 49.1% − 3.1% = 46.0%) (P = 0.004). Multivariable logistic regression analysis in relation to the pathogen spectrum and antimicrobial resistance development showed a significantly higher mortality for non‐albicans Candida spp. (P = 0.039, odds ratio [OR] = 3.32 [95% confidence interval [CI]: 1.07–10.35]), E. faecium (P = 0.009, OR = 3.73 [95% CI: 1.38–10.05]), and multi‐resistant bacteria (P = 0.007, OR = 5.08 [95% CI: 1.55–16.66]).ConclusionsAntimicrobial treatment of infected pancreatic necrosis becomes more challenging over time, owing to a change in spectrum favoring difficult‐to‐treat pathogens and an increase in multi‐resistant bacteria associated with worse clinical outcomes (World Health Organization trial registration number: DRKS00014785).

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Acute Pancreatitis

Cited by 4 publications

References 208 publications

Spontaneous Hepatic Hemorrhage: An Unexpected Complication From Enoxaparin

Spontaneous Hepatic Hemorrhage: An Unexpected Complication From Enoxaparin

Kur Ân Da İsmi̇ Zi̇kredi̇len Tek Sahâbî Zeyd B. Hâri̇se Ni̇n Hayati, Şahsi̇yeti̇ Ve İslâm a Hi̇zmetleri̇

Changes in pathogen spectrum and antimicrobial resistance development in the time‐course of acute necrotizing pancreatitis

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