Acute Parenchymal Lung Disease in Immunocompetent Patients

Tomiyama, Noriyuki; Müller, Néstor L.; Johkoh, Takeshi; Honda, Osamu; Mihara, Naoki; Kozuka, Takenori; Hamada, Seiki; Nakamura, Hajime; Akira, Masanori; Ichikado, Kazuya

doi:10.2214/ajr.174.6.1741745

Cited by 67 publications

(31 citation statements)

References 18 publications

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“…When these are present in a patchy distribution, they suggest infectious disease. (70) Hypersensitivity pneumonitis Centrilobular nodules of ground-glass opacity distributed diffusely and profusely through the Connective tissue disease-related interstitial lung disease Like drugs, systemic autoimmune diseases can produce a wide variety of histopathological patterns. (76) In patients previously diagnosed with connective tissue disease (CTD), DAD or acute OP can occur-or the pneumonitis can represent the initial manifestation of disease, especially in systemic lupus erythematosus, polymyositis, and adult-onset Still's disease.…”

Section: Pulmonary Edemamentioning

confidence: 99%

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

et al. 2008

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High-resolution computed tomography (HRCT) is the radiological imaging technique best suited to revealing changes in lung structure. Various HRCT findings, taken together, can represent typical patterns. These patterns, in conjunction with the anatomical distribution of findings and with clinical data, can narrow the differential diagnosis of diffuse interstitial lung disease and, in many cases, indicate the correct diagnosis with a high degree of accuracy. The most common HRCT patterns seen in cases of diffuse interstitial lung diseases are the nodular pattern, linear/reticular opacities, cystic lesions, ground-glass opacities and consolidations. This article reviews the correlations between HRCT patterns and pathologic findings, summarizing the most common causes, as well as detailing the methods of investigation employed in order to diagnose the most common types of chronic diffuse lung disease.Keywords: Lung diseases, interstitial/pathology; Tomography, X-Ray computed; Diagnostic techniques, respiratory system. ResumoA tomografia de alta resolução (TCAR) é a técnica de imagem radiológica que reflete mais de perto as alterações da estrutura pulmonar. Os vários achados tomográficos podem ser combinados para formar padrões típicos. Estes, conjuntamente com a distribuição anatômica dos achados, e com os dados clínicos, podem estreitar o diagnóstico das doenças intersticiais pulmonares difusas, e em vários casos sugerir o diagnóstico correto com alto grau de acurácia. Os padrões mais comuns das doenças intersticiais pulmonares difusas na TCAR são o nodular, linear e reticular, lesões císticas, opacidades em vidro fosco e consolidações. Este artigo revisa as correlações entre os padrões tomográficos na TCAR e os achados patológicos e resume as causas mais comuns e os métodos de investigação para se atingir um diagnóstico nas doenças pulmonares crônicas difusas mais comuns.Descritores: Doenças pulmonares intersticiais/patologia; Tomografia computadorizada por raios X; Técnicas de diagnóstico do sistema respiratório.* Study carried out in the

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Section: Pulmonary Edemamentioning

confidence: 99%

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

et al. 2008

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“…CT is a useful adjunct to conventional radiography in selected cases [10,12,18,19]. There is a large amount of literature indicating that CT is a sensitive method capable of imaging the lung with excellent spatial resolution, providing anatomical detail similar to that seen by gross pathological examination.…”

Section: Computed Tomographymentioning

confidence: 99%

Imaging of pneumonia: trends and algorithms

2001

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Pneumonia is one of the major infectious diseases responsible for significant morbidity and mortality throughout the world. Imaging plays a crucial role in the detection and management of patients with pneumonia. This review article discusses the different imaging methods used in the diagnosis and management of suspected pulmonary infections. The imaging examination should always begin with conventional radiography. When the results of routine radiography are inconclusive, computed tomography is mandatory. A combination of pattern recognition with knowledge of the clinical setting is the best approach to the pulmonary infectious processes.A specific pattern of involvement can suggest a likely diagnosis in many instances. In acquired immune deficiency syndrome patients, diffuse ground-glass and interstitial infiltrates are most commonly present in Pneumocystis carinii pneumonia whereas in the nonimmunosuppressed patients, a segmental lobar infiltrate is suggestive of a bacterial pneumonia. Round pneumonia is most often encountered in children than adults and is most often caused by Streptococcus pneumoniae. Different combinations of parenchymal and pleural abnormalities may be suggestive for additional diagnoses.When an infectious pulmonary process is suspected, knowledge of the varied radiographic manifestations will narrow the differential diagnosis, helping to direct additional diagnostic measures, and serving as an ideal tool for follow-up examinations.

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“…(54) For the evaluation of patients with acute diffuse pulmonary infiltrate, the most important ancillary tests are HRCT, bronchoscopy with BAL (with cytological and microbiological examination), TBB, and surgical biopsy. (55) Acute exacerbation of ILD, classically associated with IPF, is defined by the following criteria: previous or concurrent diagnosis of IPF; unexplained development or worsening of dyspnea; HRCT showing a pattern consistent with UIP and new areas of ground-glass opacity, consolidation, or both; reduced oxygenation; and exclusion of infections and other diagnoses.…”

Section: Acute Diffuse Lung Diseasementioning

confidence: 99%

Destaques das diretrizes de doenças pulmonares intersticiais da Sociedade Brasileira de Pneumologia e Tisiologia

et al. 2012

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Interstitial lung diseases (ILDs) are heterogeneous disorders, involving a large number of conditions, the approach to which continues to pose an enormous challenge for pulmonologists. The 2012 Brazilian Thoracic Association ILD Guidelines were established in order to provide Brazilian pulmonologists with an instrument that can facilitate the management of patients with ILDs, standardizing the criteria used for the diagnosis of different conditions and offering guidance on the best treatment in various situations. The objective of this article was to briefly describe the highlights of those guidelines.Keywords: Lung diseases, interstitial; Guidelines as topic; Brazil. ResumoAs doenças pulmonares intersticiais (DPIs) são afecções heterogêneas, envolvendo um elevado número de condições, cuja abordagem ainda é um grande desafio para o pneumologista. As Diretrizes de DPIs da Sociedade Brasileira de Pneumologia e Tisiologia, publicadas em 2012, foram estabelecidas com o intuito de fornecer aos pneumologistas brasileiros um instrumento que possa facilitar a abordagem dos pacientes com DPIs, padronizando-se os critérios utilizados para a definição diagnóstica das diferentes condições, além de orientar sobre o melhor tratamento nas diferentes situações. Esse artigo teve como objetivo descrever resumidamente os principais destaques dessas diretrizes.Descritores: Doenças pulmonares intersticiais; Guias como assunto; Brasil.

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Acute Parenchymal Lung Disease in Immunocompetent Patients

Abstract: High-resolution CT is helpful in the differential diagnosis of infectious from noninfectious acute parenchymal lung disease. However, high-resolution CT is of limited value in making a specific diagnosis.

Cited by 67 publications

References 18 publications

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

Imaging of pneumonia: trends and algorithms

Destaques das diretrizes de doenças pulmonares intersticiais da Sociedade Brasileira de Pneumologia e Tisiologia

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