Acute perioperative normovolaemic haemodilution in major maxillofacial surgery

Parkin, I.R.; Chiu, G.; Schwarz, P; Hodder, S.C.

doi:10.1016/j.bjoms.2008.01.002

Cited by 6 publications

(3 citation statements)

References 20 publications

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“…Patients undergoing isolated neck dissections rarely require transfusion, but if such surgical approaches are combined with ablation of the index tumour and in particular microvascular free tissue transfer allogenic blood is often indicated with it attendant problems including communicable disease transmission. In prognostic terms the immunosuppressant effects such blood transfusions have not been shown to have a detrimental impact on survival but autogenous transfusion or peri-operative normovolemic haemodilution remain viable alternatives [ 11 , 12 ].…”

Section: Pre-operative Evaluationmentioning

confidence: 99%

Prevention of complications in neck dissection

Kerawala

Heliotos

2009

Head Neck Oncol

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Section: Pre-operative Evaluationmentioning

confidence: 99%

Prevention of complications in neck dissection

Kerawala

Heliotos

2009

Head Neck Oncol

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“…There has been growing interest in reducing the exposure of patients to allogeneic blood transfusions by lowering the volume of preoperative cross‐matched blood ordering and by using other means, such as preoperative autologous blood donation, recombinant human erythropoietin administration, nutritional supplementation, and acute normovolemic hemodilution . Optimal utilization of these alternative techniques requires the identification of patients who would benefit most from their use.…”

Section: Introductionmentioning

confidence: 99%

Predictive factors for perioperative blood transfusion in neck dissection

et al. 2015

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“…Different blood conservation strategies have their own merits and drawbacks. However, none of these strategies are widely regarded as the optimal blood conservation method (8,(17)(18)(19)(20)(21). Therefore, it would be advantageous to identify the preoperative and predictable intraoperative variables predicting the need for allogenic transfusion in patients with OOSCC undergoing surgery with radical tumor resection and free flap reconstruction.…”

Section: Discussionmentioning

confidence: 99%

Developing a predictive risk score for perioperative blood transfusion: a retrospective study in patients with oral and oropharyngeal squamous cell carcinoma undergoing free flap reconstruction surgery

Su¹,

Xie²,

Cai³

et al. 2021

Ann Transl Med

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Background: A simple and accurate scoring system to predict risk of blood transfusion in patients having surgical tumor resection with immediate free flap reconstruction primary surgery for oral and oropharyngeal squamous cell carcinoma (OOSCC) is lacking. Anticipating the blood transfusion requirements in patients with oral cancer is of great clinical importance. This research aimed to propose a valid model to predict transfusion requirements in patients undergoing surgery with free flap reconstruction for an OOSCC.Methods: This retrospective study consisted of 385 patients who underwent oncologic surgery with immediate free flap reconstruction for locally advanced OOSCC from 2012 to 2019. The primary outcome measured was the exposure of patients to perioperative allogeneic blood transfusion. Based on a multivariate model of independent risk variables and their odds ratio, a blood transfusion risk score (TRS) was developed to predict the likelihood of the perioperative blood transfusion. The discriminatory accuracy of the model was evaluated using the area under the receiver operating characteristic (ROC) curve, and Youden index was used to identify the optimal cut-point.Results: Logistic regression analyses identified lymph node status, preoperative hemoglobin (Hb) levels, bone resection, osseous free tissue transfer, and operative duration were identified as independent predictors of blood transfusion. A TRS integrating these variables was separated into three categories. The TRS assessed the transfusion risk with good predictive ability, with an overall area under the ROC curve (AUC) was 0.826. At the optimal cut-point of 5.5, the TRS had a sensitivity of 72.3% and a specificity of 78.2%. The ROC analysis showed that patients with a TRS of 5.5 or more had a greater requirement for perioperative transfusion. Conclusions:The use of the integer-based TRS allowed the identification of high-risk patients who may require perioperative transfusion undergoing tumor resection surgery for the treatment of OOSCC.

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Acute perioperative normovolaemic haemodilution in major maxillofacial surgery

Cited by 6 publications

References 20 publications

Prevention of complications in neck dissection

Prevention of complications in neck dissection

Predictive factors for perioperative blood transfusion in neck dissection

Developing a predictive risk score for perioperative blood transfusion: a retrospective study in patients with oral and oropharyngeal squamous cell carcinoma undergoing free flap reconstruction surgery

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