Acute Phase Hypergylcemia among Patients Hospitalized with Acute Coronary Syndrome: Prevalence and Prognostic Significance

Mansour, Abbas Ali; Wanoose, Hameed Laftah

doi:10.5001/omj.2011.22

Cited by 17 publications

(14 citation statements)

References 35 publications

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“…Occurrence of STEMI, NSTEMI and UA in two different groups was statistically insignificant (P=0.44).Similarly, Abbas Ali Mansour et al in 2011 9 found no significant difference in occurrence of Acute Coronary Syndrome in different groups which is in concordance with our study.…”

Section: Discussionsupporting

confidence: 82%

“…In a study conducted by Abbas Ali Mansour, patients with ACS were divided into 3 groups out of which 36.2 % were non-diabetic patients without acute phase hyperglycemia, 27.2 % were Non-diabetic patients with acute phase hyperglycemia and 36.6 % were diabetic patients 9 .High prevalence of stress hyperglycemia was found in similar studies conducted by Kosiborod et al 1 .…”

Section: Discussionmentioning

confidence: 55%

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Prognostic value of stress hyperglycemia in acute coronary syndrome in non-diabetic patients

Aggarwal¹,

Goyal²,

Sikri³

et al. 2017

Int. J. Curr. Res. Med. Sci.

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Background: Any kind of stress, physical or emotional leads to increased production of ACTH, thus leading to increased glucocorticoid release and hence, hyperglycemia. Various studies suggest that the treatment of Stress Hyperglycemia has tremendous potential to reduce the morbidity and mortality among hospitalized patients with Stress Hyperglycemia. Aims: To study the prevalence and prognostic value of stress hyperglycemia in determining the cardiovascular outcome in non-diabetic acute coronary syndrome patients. Material and Methods: This study was conducted in 100 patients with no previous history of diabetes with Acute Coronary Syndrome over a period of 18 months. Stress Hyperglycemia in the acute phase of Acute Coronary Syndrome was defined as random blood glucose levels greater than or equal to 140 mg/dl. Patients were divided into two groups A and B on the basis of random blood sugar as normoglycemics and those with Stress Hyperglycemia, respectively. These groups were compared to demonstrate the correlation between stress hyperglycemia and cardiovascular outcome of heart failure, arrhythmias, cardiogenic shock or death. The data was collected and statistically analysed. Results: Out of 100 patients of acute coronary syndrome with no previous history of diabetes, 38 % were found to be having stress hyperglycemia. Heart failure, arrhythmia, shock and death occurred in 57.89%,13.16 % 13.16 %, 21.05% of Stress Hyperglycemic patients as compared to only 16.12%,4.83%, 8.06 %, 6.45 % in normoglycemic patients, respectively. Summary and Conclusion: There is high prevalence (38%) of Stress Hyperglycemia in Acute coronary syndrome patients and is associated with adverse outcomes such as heart failure, arrhythmia, cardiogenic shock and death.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 55%

Prognostic value of stress hyperglycemia in acute coronary syndrome in non-diabetic patients

Aggarwal¹,

Goyal²,

Sikri³

et al. 2017

Int. J. Curr. Res. Med. Sci.

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“…Braeley et al [6] showed that increased BG level causes harm through a variety of ways in critically ill. Recent study of Mansour et al [7] confirmed that increased BG level (≥ 7.8 mmol/L) is an unfavorable prognostic factor also in patients with ACS. Hyperglycemia in these patients leads to higher levels of cardiac necrosis markers and lower left ventricular ejection fraction [9,22].…”

Section: Discussionmentioning

confidence: 94%

“…It has been shown that for patients with AMI, increased admission blood glucose (ABG) level has been associated with adverse outcomes including death [7]. The prevalence of admission hyperglycemia (glucose levels ≥ 7.8 mmol/L) in different epidemiological studies ranges from 51% to > 58% of patients hospitalized with AMI [8].…”

Section: Introductionmentioning

confidence: 99%

Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock

et al. 2015

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“…Hasil ini tidak sesuai dengan penelitian sebelumnya yang menyebutkan untuk pasien SKA dengan hiperglikemia lebih banyak terdapat pada diagnosis STEMI yaitu terdapat 106 (59.9%) pasien, sedangkan untuk NSTEMI dan UAP hanya memperoleh masing-masing 26 (14.7%) dan 45 (25.4%) pasien. Dan pada pasien SKA tanpa hiperglikemia lebih banyak terdapat pada diagnosis STEMI juga yaitu sebesar 51 (46.4%) pasien dengan nilai p=0.071 (Mansour and Wanoose, 2011).…”

Section: Hasil Dan Pembahasanunclassified

Hiperglikemia Sebagai Prediktor Keberhasilan Pengobatan Pasien Dengan Sindrom Koroner Akut Di Rsud X Surakarta

2018

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ABSTRAKSindrom Koroner Akut atau acute coronary syndrome (ACS) dengan hiperglikemia pada saat masuk memiliki rerata mortalitas yang lebih tinggi, pada penelitian terbaru. Hiperglikemia pada pasien dengan ACS digambarkan sebagai respon akut dari keadaan hiperadrenergik dengan peningkatan risiko trombosis, sehingga bisa memperburuk kondisi pasien ACS selama dirawat di rumah sakit. Tujuan penelitian ini untuk mengetahui perbedaan lama tinggal dan mortalitas pada pasien ACS dengan stres hiperglikemia dan tanpa hiperglikemia stres. Jenis penelitian ini adalah penelitian observasional analitik dengan pendekatan cross sectional. Subjek penelitian adalah pasien ACS non-diabetes di RSUD X Surakarta. Data diperoleh dari rekam medis dengan teknik purposive sampling, dianalisis dengan uji Mann-Whitney. Subjek penelitian sebanyak 68 pasien, 34 pasien ACS dengan hiperglikemia dan 34 pasien ACS tanpa hiperglikemia. Hasil penelitian ini menyatakan ada perbedaan durasi lama tinggal pasien ACS dengan dan tanpa hiperglikemia(p = 0,002) dan tidak ada perbedaan rerata mortalitas diantara keduanya. Kata kunci: Sindrom Koroner Akut, Hiperglikemia, Lama Rawat Inap, MortalitasABSTRACT Acute Coronary Syndrome (ACS) in recent studies has been associated with hyperglycemia at the time of admission with higher mortality rates. Hyperglycemia in patients with ACS described as an acute response from a hyperadrenergic state with an increased risk of thrombosis, so it could worsen the condition of the patient ACS during the hospital stay. Aims of this study are to know differences in length of stay and mortality in ACS patients with hyperglycemia stress and without hyperglycaemia stress. This was an analytical observational research design with cross sectional approach. The subjects were non diabetic ACS patient in RSUD X Surakarta. Data were obtained from medical record with purposive sampling technique, analyzed by Mann-Whitney test. Subjects were 68 patients, 34 patients ACS with hyperglycemia and 34 patients ACS without hyperglycemia. There is a difference in duration long of stay ACS patients with and without hyperglycemia (p = 0.002) and there is no difference in mortality.

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Acute Phase Hypergylcemia among Patients Hospitalized with Acute Coronary Syndrome: Prevalence and Prognostic Significance

Abstract: Admission acute phase hyperglycemia of ³140 mg/dl (7.8 mmol/L) was associated with heart failure in this study.

Cited by 17 publications

References 35 publications

Prognostic value of stress hyperglycemia in acute coronary syndrome in non-diabetic patients

Prognostic value of stress hyperglycemia in acute coronary syndrome in non-diabetic patients

Admission hyperglycemia in patients with acute coronary syndrome complicated by cardiogenic shock

Hiperglikemia Sebagai Prediktor Keberhasilan Pengobatan Pasien Dengan Sindrom Koroner Akut Di Rsud X Surakarta

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