Acute phase reactants and lipid profile in acute chest pain presentations: a multimarker approach

Anees, Syyeda; Fatima, Jabeen; Hyder, Abbas

doi:10.18203/2320-6012.ijrms20162290

Cited by 2 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The deposition of LDL into the sub-endothelial space creates a tendency for LDL to be exposed to oxidation. Under conditions of high oxidative stress there is increased peroxidation of lipoprotein phospholipids, thereby increasing the LDL-uptake by macrophages with increased foam cell formation and atherosclerosis (19) Atherosclerosis is a chronic disease caused by excessive accumulation of lipids in macrophages and smooth muscle cells, resulting in the formation of foam cells and in cell death. Oxidative alteration of low-density lipoproteins (LDL) is supposed to play a key role in the atherogenesis.…”

Section: Discussionmentioning

confidence: 99%

Biochemical Parameters in Acute Myocardial Infarction with or Without Co-Morbidities

More¹

2017

jmscr

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Biochemical Parameters in Acute Myocardial Infarction with or Without Co-Morbidities

More¹

2017

jmscr

View full text Add to dashboard Cite

“…According to the studies, under hypoxic stress interleukin-6 is produced in different cells i.e. endothelial cells, monocytes as well as in cardiac myocytes and this interleukin-6 then leads to the production of CRP in liver cells that leads to raised CRP levels in the body 8,11 .…”

Section: Discussionmentioning

confidence: 99%

“…C-reactive protein (CRP) is one of the most important inflammatory biomarkers and that it is an acute phase reactant. According to the studies, it is a sensitive and accurately reflects the acute phase response in certain cardiovascular diseases including heart failure 7,8 . In the current clinical practices, CRP is widely used for diagnosis and management of these cases.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Raised CRP in Acute Heart Failure

Sarwar

Rashid

2020

Pak Postgrad Med J.

View full text Add to dashboard Cite

C-reactive protein (CRP) is a marker for cardiovascular and cerebrovascular diseases. It is also proven that it has role in long-term development of heart failure and mortality in patients with cardiovascular diseases. Objective: To analyze the CRP levels in patients presenting with acute heart failure and determine the frequency of patients with raised CRP levels. Material and Methods: This cross-sectional study was conducted at Punjab Institute of Cardiology for a period of six months after approval from the hospital ethical committee. Three hundred and forty-five patients presenting with acute heart failure were taken. After Informed consent, their venous blood samples were drawn for measurement of CRP levels. All the data was collected on a predefined proforma. The data was entered and analyzed in SPSS Ver. 23.0. Results: The mean age of patients was 45.5 l ± 10.64 years. There were 192 (55.7%) males and 153(44-3%) females. The mean duration of heart failure was 6.46 ± 3.53 hours. The mean CRP in these cases was 6.27 ± 4.70 mg/L. There were 153(44.3%) patients who had raised CRP while 192(55.7%) patients had normal CRP levels. Conclusion: Increased CRP levels were seen in high number of cases and this may be established as significant risk factor for in hospital mortality. Particular attention should be given for prior management in presence of raised CRP.

show abstract

Acute phase reactants and lipid profile in acute chest pain presentations: a multimarker approach

Cited by 2 publications

References 26 publications

Biochemical Parameters in Acute Myocardial Infarction with or Without Co-Morbidities

Biochemical Parameters in Acute Myocardial Infarction with or Without Co-Morbidities

Frequency of Raised CRP in Acute Heart Failure

Contact Info

Product

Resources

About