Acute pseudo-obstruction of the colon in thermally injured patients

Lescher, Thomas J.; Teegarden, David K.; Pruitt, Basil A.

doi:10.1007/bf02586410

Cited by 24 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A feature of stress ulceration that assumes particular importance when one is studying the etiology of this condition is the sparing of the antral mucosa by the acute lesions. Another point worthy of emphasis is the fact that low-flow states can cause acute mucosal injury in the small intestine [2], particularly the terminal ileum and/or colon, as well as in the gastric mucosa. These intestinal lesions may occur in association with, or independently from, the gastric lesions.…”

Section: Supported In Part By United States Public Health Service Gra...mentioning

confidence: 99%

“…In order to test this hypothesis a series of laboratory investigations was undertaken. Using a rat model [2,3], we were able to demonstrate that acute nutritional depletion in conjunction with bile salt wash was associated with hydrogen ion back-diffusion and severe gastric erosions. The semistarved animals had markedly decreased gastric protein synthesis as measured by 15N glycine incorporation into gastric mucosal tissue.…”

Section: Invited Commentarymentioning

confidence: 99%

See 1 more Smart Citation

Role of gastric mucosal energy metabolism in the etiology of stress ulceration

Menguy

1981

World j. surg.

View full text Add to dashboard Cite

It is generally agreed that mucosal ischemia of the gastrointestinal tract is one of the major consequences of the low‐flow state, be it due to blood loss, fluid loss, or sepsis. In the present paper, arguments are presented in favor of the hypothesis that stress‐induced mucosal injury which tends to occur preferentially in the proximal stomach, duodenum, and terminal ileum results from a mucosal energy deficit severe enough to cause cell death.

show abstract

Section: Supported In Part By United States Public Health Service Gra...mentioning

confidence: 99%

Section: Invited Commentarymentioning

confidence: 99%

Role of gastric mucosal energy metabolism in the etiology of stress ulceration

Menguy

1981

World j. surg.

View full text Add to dashboard Cite

show abstract

Ischemic Necrotic Bowel Disease in Thermal Injury

Kowal-Vern

McGill²,

Gamelli³

1997

Arch Surg

View full text Add to dashboard Cite

The severity of thermal injury and systemic infection are risk factors for the development of INBD. This entity is more frequent currently because of increased survival of the more severely injured patients. Systemic infection may alter the integrity of the bowel, which becomes less "tolerant" of enteral feedings. The role of large-volume high-density enteral feedings as a usually associated event in these patients remains speculative.

show abstract