Acute psychosis following baclofen overdose

Abstract

Baclofen is widely used as a muscle relaxant in neurological and other physical health conditions, as well as for its anticraving effects in substance use disorder. Here the authors describe a case of baclofen overdose resulting in acute psychosis. Clinicians need to consider this in the differential diagnosis of first episode psychosis presentations, as unrecognised, and untreated baclofen overdose‐induced psychosis can be associated with significant morbidity and potential mortality.