Acute pyelonephritis revealing a rare renal collision tumor of papillary and chromophobe cell carcinoma with sarcomatoid features

Abstract

A 59-year-old male patient was admitted to the emergency room with febrile right flank pain. The computed tomography scan and the magnetic resonance imaging had objectified lesion image occupying the upper half of the right kidney, measuring 82 mm, suggesting an infectious origin without excluding the infected tumor. He was put under antibiotics. A percutaneous biopsy revealed renal cell carcinoma with suppurative tumor necrosis. He underwent a right radical nephrectomy. The histopathological study revealed a collision tumor of papillary, chromophobe renal cell carcinoma and sarcomatoid dedifferentiation. It is the second case reported in English literature to date.

Sporadic unilateral papillary renal cell carcinoma masquerading pyelonephritis: A case report

“… 11 Also, Boukhannous et al reported a unilateral RCC masquerading as pyelonephritis. 3 Like Boukhannous et al, our patient had unilateral papillary RCC presenting with features of pyelonephritis. Our management was focused on obstructive pyelonephritis.…”

“…reported a unilateral RCC masquerading as pyelonephritis 3. Like Boukhannous et al, our patient had unilateral papillary RCC presenting with features of pyelonephritis.…”

“… 2 Rarely, RCC presents with features suggestive of acute pyelonephritis. 3 RCC related to inflammatory conditions such as abscess formations or pyelonephritis may delay the cancer diagnosis and lead to improper management. Furthermore, inflammatory and neoplastic systemic signs overlap, and radiologic studies may sometimes fail to differentiate between these two disease entities.…”

“…Furthermore, inflammatory and neoplastic systemic signs overlap, and radiologic studies may sometimes fail to differentiate between these two disease entities. 3 Herein, we present the case of a 62‐year‐old male with left obstructive pyelonephritis, later identified as unilateral sporadic renal papillary cell carcinoma.…”

“…Papillary RCC, a subtype of RCC, accounts for about one‐eighth of all cases and is frequently associated with advanced kidney disease 2 . Rarely, RCC presents with features suggestive of acute pyelonephritis 3 . RCC related to inflammatory conditions such as abscess formations or pyelonephritis may delay the cancer diagnosis and lead to improper management.…”