“…As awareness of the toxicity of contrast media has grown over the past few years, so have estimates of the frequency of complica tions. Several predisposing factors have been implicated; the most significant are preexisting renal insufficiency [8,18,20,22,[29][30][31][32][33] and diabetes mellitus [3,5,11,18,20,25,31,33]. Of the more than 250 published cases of con trast nephropathy, over 90% involved patients with renal insufficiency and over 50% involved patients with dia betes mellitus.…”