Acute Renal Failure in Lung Transplantation: Incidence, Correlation With Subsequent Kidney Disease, and Prognostic Value

Castro, A. González; Llorca, Javier; Cañas, B. Suberviola; Fernández-Miret, Borja; Zurbano, Felipe; Miñambres, Eduardo

doi:10.1016/s1579-2129(08)60061-0

Cited by 10 publications

(8 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When evaluating renal function status on arrival in the ICU immediately after LT, kidney failure was not correlated with 30-day mortality in the study by González Castro et al (15). However, when stratified as acute renal failure requiring and not requiring dialysis in the first 2 postoperative weeks, the former was as significant marker of mortality in the study by Rocha et al (16).…”

Section: Discussionmentioning

confidence: 94%

Prognostic Factors in Lung Transplantation: The Santa Casa de Porto Alegre Experience

et al. 2011

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 94%

Prognostic Factors in Lung Transplantation: The Santa Casa de Porto Alegre Experience

et al. 2011

View full text Add to dashboard Cite

show abstract

“…However, highlighting again the importance of AKI beyond those who require RRT, even patients with less severe AKI stayed in the hospital longer than those with no AKI. 6,7 Outside of in-hospital events, a growing body of evidence suggests that AKI is associated with long-term ad- verse outcomes and is not solely limited to those with the most severe forms of AKI requiring dialysis. 15 A recent meta-analysis by Coca et al 9 showed that all severities of AKI, even the mildest forms are associated, with long-term mortality.…”

Section: Discussionmentioning

confidence: 99%

“…They concluded that though AKI (defined by post-operative doubling of serum creatinine) occurred in 56% after lung transplantation, only patients who required dialysis (8%) had significant peri-operative morbidity and long-term mortality. Similarly, Castor et al 7 reported that AKI, defined by decline in estimated glomerular filtration rate (eGFR) in the first 24 hours after transplantation, occurs in 59% of patients but found no association between 1-month mortality and the degree of perioperative renal failure.…”

mentioning

confidence: 99%

Short-term and long-term outcomes of acute kidney injury after lung transplantation

Wehbe

Brock

Budev

et al. 2012

The Journal of Heart and Lung Transplantation

View full text Add to dashboard Cite

“…Twelve (13%) patients required RRT (continuous hemofiltration for 6 patients, intermittent hemodialysis for one patient, and both techniques for 5 patients). RRT was initiated a median of 7 [3][4][5][6][7][8][9][10][11][12][13][14] days after LT for a median duration of 8 [2][3][4][5][6][7][8][9][10][11][12][13][14] days. Characteristics of patients with KDIGO 3 AKI are described in Table 4.…”

Section: Characteristics Of Patients With Kdigo 3 Akimentioning

confidence: 99%

Acute Kidney Injury After Lung Transplantation: Perioperative Risk Factors and Outcome

Atchade

Barour

Tran-Dinh

et al. 2020

Transplantation Proceedings

View full text Add to dashboard Cite

BACKGROUND Acute kidney injury (AKI) is associated with increased short-term and long-term mortality and morbidity after lung transplantation (LT). The primary objective of this study was to analyze the perioperative factors associated with AKI according to KDIGO criteria during hospitalization in an intensive care unit (ICU) after LT. METHODS This was a single-center observational, prospective study. AKI was defined according to KDIGO criteria. Results are expressed as median, interquartile range, absolute numbers and percentages. Statistical analyses were performed using Chi-square test, Fisher's exact test and Mann-Witney U test (p<0.05 was considered to be significant). Multivariate analysis was performed to identify independent risk factors. RESULTS Between January 2016 and April 2018, 94 patients (pts) underwent LT (70% bilateral LT). AKI occurred during ICU stay in 46 pts (49%). KDIGO 1 AKI was observed in 16 pts (17%), KDIGO 2 in 14 pts (15%), and KDIGO 3 in 16 pts (17%) including 12 pts (75%) who required renal replacement therapy (RRT). AKI occurred before the fifth day after surgery for 38 patients (82% of the AKI patients). On multivariate analysis, independent factors associated with AKI were bilateral LT and mechanical ventilation (MV) > 3 days (OR 4.26 95%CI 1.49; 13.63 p=0.010 and OR 5.56 1.25; 11.47 p=0.018, respectively). AKI and the need for RRT were significantly associated with ICU mortality, 28-day mortality and one-year mortality. CONCLUSION AKI is common during ICU stay after LT, especially after bilateral LT and is associated with prolonged MV, and increased short-term and long-term mortality. Background Acute kidney injury (AKI) is a common complication after lung transplantation (LT), observed in 39 to 69% of LT recipients (1-4) and leading to renal replacement therapy (RRT) in 5 to 13% of cases (4,5).

show abstract

Acute Renal Failure in Lung Transplantation: Incidence, Correlation With Subsequent Kidney Disease, and Prognostic Value

Cited by 10 publications

References 18 publications

Prognostic Factors in Lung Transplantation: The Santa Casa de Porto Alegre Experience

Prognostic Factors in Lung Transplantation: The Santa Casa de Porto Alegre Experience

Short-term and long-term outcomes of acute kidney injury after lung transplantation

Acute Kidney Injury After Lung Transplantation: Perioperative Risk Factors and Outcome

Contact Info

Product

Resources

About