Acute Renal Failure in Pregnancy

Kleinknecht, D; G, Bochereau; Chauveau, Paul

doi:10.1007/978-1-4613-2841-4_17

Acute Renal Failure 1984

DOI: 10.1007/978-1-4613-2841-4_17

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Acute Renal Failure in Pregnancy

D Kleinknecht¹,

Bochereau G²,

Paul Chauveau³

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1993

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Acute Renal Failure in Pregnancy

et al. 1993

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Between 1982 and 1992, 18 cases of pregnancy-related acute renal failure (PR-ARF) were observed (9% of the total number of ARF). Mean age of the women was 32 years (22-40 years). Uterine hemorrhage and preeclampsia/eclampsia were the major causes of ARF, accounting for 61% of the cases. Patchy renal cortical necrosis was suspected in 2 cases whereas signs of disseminated intravascular coagulation (DIC) or microangiopathic hemolytic anemia were present in 6 (33%) and 9 (50%) cases, respectively. Ten women required hemodialysis; and 6 of them, additional plasma exchange sessions. Five patients (28%) died during the acute phase of the illness, mainly due to brain damage, hepatic failure, and sepsis. Among the survivors, a complete (61.5%) or partial recovery (23.1%) was usually seen, but irreversible renal failure was recorded in 2 cases with postpartum hemolytic uremic syndrome (HUS). Short-lasting oligoanuria (< 3 days) represents a good prognostic index. However, the presence of vascular injury (cortical necrosis, HUS) seems to carry a poor prognosis. In conclusion, PR-ARF is still a critical occurrence, associated with serious prognosis for both women and kidneys. So far, the most effective measures remain the careful prevention and the aggressive management of the obstetric complications.

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Acute Renal Failure in Pregnancy

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Acute Renal Failure in Pregnancy

Cited by 1 publication

References 32 publications

Acute Renal Failure in Pregnancy

Acute Renal Failure in Pregnancy

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