Acute renal failure in the newborn: Incidence and outcome

Airede, A'ki; Bello, Mustapha; Weerasinghe, H. D.

doi:10.1111/j.1440-1754.1997.tb01589.x

Cited by 48 publications

(43 citation statements)

References 22 publications

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“…It was 53% in a study done by Airede A et al 9 and Mortazavi F et al 18 found 29.8% babies with perinatal asphyxia developed AKI. As kidneys are very sensitive to oxygen deprivation, renal insufficiency may occur within 24 hours of a hypoxic ischemic episode, which if prolonged, may lead to irreversible cortical necrosis.…”

Section: Discussionmentioning

confidence: 91%

“…Stapleton et al 1 , Ghaebaghi MM et al 8 , Airede A et al 9 and Andreoli SP 10 found that the incidence of AKI was 3-8% in sick neonates. In several studies 8,9,17 it was found that predominantly male and term babies developed renal impairment. In our study, similar findings were found.…”

Section: Discussionmentioning

confidence: 98%

“…Although non-oliguric neonatal kidney injury is being detected with increasing frequency. 1,7 Study done by Stapleton FB et al 1 , Gharehbaghi MM 8 , Airede A et al 9 and Andreoli SP 10 found that the incidence of acute kidney injury was 3% to 8% in sick neonate. A wide variety of predisposing factors such as asphyxia (40%), sepsis (22%), feeding problems (18%), heart failure, prematurity and urogenital anomalies are commonly reported causes of AKI in the developed countries.…”

Section: Introductionmentioning

confidence: 99%

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Acute Kidney Injury in Sick Neonate: Incidence and Outcome

Halder¹,

Hoque

Rahman³

et al. 2017

J. Bangladesh Coll. Phys.

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Introduction: Acute kidney injury (AKI) is an important clinical problem in sick neonate. In most patients, AKI accompanies with a predisposing factor such as sepsis, asphyxia and surgery. The aims of this study were to determine the incidence, associated contributing factors and short term outcome of AKI in hospitalized newborn infants. Materials and Methods: This prospective cohort study was done in Dhaka Shishu Hospital from March 2011 to September 2011. This study included 300 sick neonates admitted during the study period. AKI was defined when serum creatinine level >1.5 mg/dl and BUN was >20 mg/dl on two separate occasions at 24 hours apart. Oliguria was defined as urine output <1ml/kg/ hr. Medical records of those patients were reviewed and data were analyzed using SPSS software.Results: Fourteen babies (4.66%) out of 300 sick neonates had AKI, of whom 64.2% were male and 35.7% female. The term and preterm neonates were 71% and 29% respectively. While a normal birth weight was observed in 57% cases, 35% had low birth weight and 7.14% had very low birth weight. Sepsis was the most common (71%) association of AKI, followed by perinatal asphyxia (52%). All patients had more than one predisposing factors. Frequency of oliguric kidney injury was 57% and non-oliguric was 43%. Mortality among the hospitalized neonate with AKI was 21%.Conclusion: This study showed that in a tertiary care hospital AKI is not uncommon (4.66%) in neonatal care unit. It is associated with some preventable conditions such as sepsis, perinatal asphyxia and shock. Outcome is poor in sick neonates with AKI (21% mortality) in comparison to sick neonates without AKI (10.3%).

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Acute Kidney Injury in Sick Neonate: Incidence and Outcome

Halder¹,

Hoque

Rahman³

et al. 2017

J. Bangladesh Coll. Phys.

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“…Esta investigación encontró un 38.4% de prevalencia de distrés respiratorio tipo I (P=0.01); de éstos, el 15.4% fueron tratados con terapia diálítica. De acuerdo a la biliografía consultada, la sepsis, asfixia e hipoxia son considerados importantes factores de riesgo [10][11][12].…”

Section: Discussionunclassified

Falla Renal Aguda Y Factores De Riesgo en Neonatos en El Hospital “José Carrasco Arteaga”

et al. 2016

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“…13 Kondisi yang tidak menguntungkan tersebut menyebabkan fungsi ginjal pada bayi lebih mudah terganggu terutama pada keadaan stres yang dapat mempengaruhi proses metabolisme dan homeostasis. 20 Gangguan fungsi ginjal pada tahap dini bersifat ringan dengan gejala azotemia prerenal yaitu kenaikan kadar kreatinin dan ureum serum akibat hipoperfusi di daerah korteks. Tahap selanjutnya gangguan bersifat sedang yang disebut GGA prerenal yang disebabkan hipoperfusi di daerah medula.…”

Section: Diskusiunclassified

Hubungan Asfiksia Neonatorum dengan Gangguan Fungsi Ginjal pada Bayi Baru Lahir

Umboh¹

2016

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Asfiksia neonatorum merupakan problem kesehatan pada bayi baru lahir yang dapat menyebabkan gagal ginjal akut jika tidak ditangani dengan baik. Tujuan: untuk mengetahui hubungan antara derajat asfiksia neonatorum dengan derajat gangguan fungsi ginjal Metoda: penelitian analitik observasional pada bayi baru lahir di bangsal Neonatologi Bagian IKA/RSUP Manado antara bulan Agustus 1997-Februari 1998 yang memenuhi kriteria dilakukan pengukuran kadar ureum dan kreatinin serum serta penentuan laju filtrasi glomerulus (LFG). Data dianalisis dengan uji Anova dan Chi-Square. Hasil: di antara 129 bayi baru lahir yang memenuhi kriteria terdiri dari 49 bayi sehat, 50 asfiksia ringan-sedang, dan 30 asfiksia berat. Terdapat perbedaan bermakna kadar serum ureum dan kreatinin serta LFG antara kelompok bayi sehat dengan asfiksia berat dan antara kelompok asfiksia ringan-sedang dengan asfiksia berat (p<0,01). Lima dari 30 kasus asfiksia berat mengalami gagal ginjal akut dan terdapat hubungan bermakna antara derajat asfiksia dengan derajat gangguan fungsi ginjal (p<0,01). Kesimpulan: terdapat perbedaan antara kadar ureum dan kreatinin serum serta LFG antara bayi asfiksia berat dengan bayi sehat dan asfiksia ringan-sedang. Terdapat pula hubungan antara derajat asfiksia dengan derajat gangguan fungsi ginjal.Kata kunci: bayi baru lahir -asfiksia -gangguan fungsi ginjal Sari

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Acute renal failure in the newborn: Incidence and outcome

Cited by 48 publications

References 22 publications

Acute Kidney Injury in Sick Neonate: Incidence and Outcome

Acute Kidney Injury in Sick Neonate: Incidence and Outcome

Falla Renal Aguda Y Factores De Riesgo en Neonatos en El Hospital “José Carrasco Arteaga”

Hubungan Asfiksia Neonatorum dengan Gangguan Fungsi Ginjal pada Bayi Baru Lahir

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