Acute respiratory tract infections among hospitalized Palestinian patients: a retrospective study

Seir, Rania Abu; Njoum, Wafa'; Najajrah, Rawan; Najjar, Dania; Ashour, Mariam; Asakra, Bassam; Samman, Nahla; Najjar, Osama

doi:10.21203/rs.2.9815/v1

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…It is noticed that from our results, the gene mutations and polymorphism in all markers are more in sample one and sample two (cases) than in sample three (control). [20] showed that gene mutations play an important role in the susceptibility of patients to pneumonia and sepsis. Also discussed the effect of genetic polymorphisms and their positive impact on calcitonin and CRP levels in patients with infection [21,22].…”

Section: Dna Sequencingmentioning

confidence: 99%

PCT, CPT, S-TREM1 and Neopetrin as inflammatory biomarkers Detection, DNA sequencing, 3D Protein and recording a new gene in cancer children with Respiratory tract infection

2023

JPTCP

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The aim of this study was to determine molecular detection of inflammatory biomarkers (PCT, CPT, S-TREM1 and Neopetrin) by using DNA sequencing, 3D Protein to give acknowledge about the roles of these biomarkers among cancer's patients with Respiratory tract Basrah province. DNA sequencing of PCT, CPT, S-TREM1, and Neopetrin has shown that there is a convergence between studied PCT and that of the Gen Bank database (NCBI) with identity 91/96 (95%) in forward PCT. A case-control study included 100 confirmed cancer's patients with Respiratory infection and 100 children as a control group. There was a convergence between studied CPT isolated and that of the Gen Bank database (NCBI) with identity 186/190(98%) in forward CPT that had been recorded four mutations appeared in (GGG to GGC), (GTA to GTC), (GGT to GGG) and (CC-to CCC). The forward CPT shown an identity144/145(99%) when compared with Gen Bank database (NCBI) one mutations reported as (CC-to CCC), (TCT to TCG), (GT-to GTG) and (TG-to TGG) in isolated s-trem1 that had been recorded. The reverse CPT had an identity 344/349 (99%), which is similar to that of the Gen Bank data. There was a convergence between studied Neopeterin isolated and that of the GenBank database (NCBI) with identity 166/167(99%) in forward Neopetrin that had been recorded one mutation appeared in (TGA to TG-). The reverse s-trem1 shown an identity 327/328(99) when compared with Gen Bank database that found one mutations was, (CGC to CG-). Neopetrin shown an identity 166/169(98%) when compared with Gen Bank database (NCBI) three mutations reported as (GGT to GGG), (TG-to TGT), (GA to GA-) and (TGA to TG-). No previous studies about the same this mutation in biomarkers. The present study sequencing of PCT, CPT, S-TREM1 and Neopetrin that showed partial a convergence between study PCT isolated and that of the GenBank database (NCBI) with identity 47/47(100%) PCT. A four mutations appeared as (S to P), (Y to S), (Ito GAB) and (R to Q). There convergence between study S-TREM1 isolated and that of the GenBank database (NCBI) with identity 71/74(96%) in S-TREM1 had a three mutations appeared as (M to I), (I to G) and (E to D). No previous studies interested studied in 3D protein with biomarkers. Neopetrin isolated and Nmethylenyl methionine isolated showed high convergence between the two, with identity 103/104 (99%) and 99% convergence.

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Section: Dna Sequencingmentioning

confidence: 99%

PCT, CPT, S-TREM1 and Neopetrin as inflammatory biomarkers Detection, DNA sequencing, 3D Protein and recording a new gene in cancer children with Respiratory tract infection

2023

JPTCP

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“…Children and the elderly were the most affected with RTIs. e elderly population (≥60 years old) had the highest rates [21].…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Attitudes Regarding Seasonal Influenza and Influenza Vaccination among Patients and Their Companions in North Palestine Hospitals

Alawneh

Al-Sayeh

Zaid

et al. 2021

Advances in Public Health

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Background. Seasonal influenza is a common highly infectious disease that can affect the upper and lower airway in children and adults mainly in wintertime which is caused by many different influenza viruses and, in some cases, may cause serious complications such as pneumonia. We conducted this study to assess the knowledge and attitudes among patients and their companions in North Palestine hospitals regarding seasonal influenza and influenza vaccination and factors influencing the uptake of this vaccine so that we can identify gaps in their knowledge and give feedback to health authorities for future quality improvement projects by increasing awareness of its effectiveness and safety. Methods. A cross-sectional 17-item survey included randomly selected samples of 327 North Palestinian patients and their companions at North Palestine hospitals. Result. A total of 327 completed questionnaires were received with a response rate of 92%. Of these, 129 participants (39.4%) believed that influenza is the same as common cold. The majority of participants (85.3%) had heard of the influenza vaccine before. Although nearly half of them (53.6%) believed that the influenza vaccine is safe, only 112 (34.7%) of the participants considered vaccination an effective means in preventing serious influenza-related complications and only 89 (27.2%) participants were previously vaccinated. The main reasons for not being vaccinated included that vaccination is not necessary because flu is not a serious disease (67%), concerns about vaccine efficacy and its side effects (25.6%), fear of needles and injection (25.2%), and 17.8% of the participants believed that this vaccine is expensive. Conclusion. The uptake and knowledge of the influenza vaccine among Palestinians are low. Vaccinated participants in our survey showed a higher level of knowledge compared to nonvaccinated participants. Half of the participants believed in the safety of the vaccine and one-third of them believed in its efficacy in preventing flu illness and its complications. Extensive and sustained efforts are needed by public health programs to promote the flu vaccine among the public by increasing awareness of its effectiveness and safety.

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Acute respiratory tract infections among hospitalized Palestinian patients: a retrospective study

Cited by 2 publications

References 14 publications

PCT, CPT, S-TREM1 and Neopetrin as inflammatory biomarkers Detection, DNA sequencing, 3D Protein and recording a new gene in cancer children with Respiratory tract infection

PCT, CPT, S-TREM1 and Neopetrin as inflammatory biomarkers Detection, DNA sequencing, 3D Protein and recording a new gene in cancer children with Respiratory tract infection

Knowledge and Attitudes Regarding Seasonal Influenza and Influenza Vaccination among Patients and Their Companions in North Palestine Hospitals

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