Acute rheumatic fever: an important differential diagnosis of septic arthritis

Mataika, Reapi L.; Carapetis, Jonathan R.; Kado, Joseph; Steer, Andrew C.

doi:10.1093/tropej/fmm116

Cited by 12 publications

(6 citation statements)

References 5 publications

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“…The reasons for this change in epidemiology are not clear. However, our data might underestimate the true incidence of ARF in Fiji because our study focused on inpatient admissions and therefore did not detect outpatient presentations, 13 , 14 or because cases of ARF are not being recognised by health care workers, 15 , 16 or because some cases of ARF are very mild and these patients do not present for medical care 4 …”

Section: Discussionmentioning

confidence: 89%

Acute rheumatic fever and rheumatic heart disease in Fiji: prospective surveillance, 2005–2007

Steer

Kado

Jenney

et al. 2009

Medical Journal of Australia

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Objectives: To determine the incidence and clinical features of acute rheumatic fever (ARF) in Fiji, and the clinical features of patients presenting to hospital in Fiji with rheumatic heart disease (RHD). Design and setting: A prospective surveillance study at the Colonial War Memorial Hospital in Suva over a 23‐month period from December 2005 to November 2007. Main outcome measures: Incidence of ARF; clinical features of ARF and RHD. Results: The average annualised incidence of definite cases of ARF in children aged 5–15 years was 15.2 per 100 000 (95% CI, 9.0–22.6). The clinical features of ARF were similar to those in classic descriptions. Carditis was very common, occurring in 79% of cases. There were 103 admissions for RHD in which detailed information was collected, with the most common reason for admission being cardiac failure (51%). The median age at admission with RHD was 26.8 years, and there were 10 deaths of patients with RHD (case fatality rate, 9.7%). Conclusions: Although apparently declining in incidence since the middle of the 20th century, ARF remains a significant health problem in Fiji. RHD affects young people, leading to premature morbidity and mortality. There is an urgent need for effective control of ARF and RHD in Fiji.

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Section: Discussionmentioning

confidence: 89%

Acute rheumatic fever and rheumatic heart disease in Fiji: prospective surveillance, 2005–2007

Steer

Kado

Jenney

et al. 2009

Medical Journal of Australia

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“…[35] The Jones Criteria have been revised and updated several times, and some countries have adapted them for their own circumstances,[836] but there continues to be cases of under- and overdiagnosis, often with tragic consequences. [37] Moreover, there is no intervention currently available that is known to alter the potential for RHD to develop following an episode of ARF. [8] Studies of immunomodulatory agents were largely undertaken several decades ago, or more recently have been relatively small and/or based on a crude understanding of ARF pathogenesis.…”

Section: Challenge 3: Better Understanding Of Disease Pathogenesis Wmentioning

confidence: 99%

Global research priorities in rheumatic fever and rheumatic heart disease

Carapetis

Zühlke

2011

Ann Pediatr Card

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We now stand at a critical juncture for rheumatic fever (RF) and rheumatic heart disease (RHD) control. In recent years, we have seen a surge of interest in these diseases in regions of the world where RF/RHD mostly occur. This brings real opportunities to make dramatic progress in the next few years, but also real risks if we miss these opportunities. Most public health and clinical approaches in RF/RHD arose directly from programmes of research. Many unanswered questions remain, including those around how to implement what we know will work, so research will continue to be essential in our efforts to bring a global solution to this disease. Here we outline our proposed research priorities in RF/RHD for the coming decade, grouped under the following four challenges: Translating what we know already into practical RHD control; How to identify people with RHD earlier, so that preventive measures have a higher chance of success; Better understanding of disease pathogenesis, with a view to improved diagnosis and treatment of ARF and RHD; and Finding an effective approach to primary prevention. We propose a mixture of basic, applied, and implementation science. With concerted efforts, strong links to clinical and public health infrastructure, and advocacy and funding support from the international community, there are good prospects for controlling these RF and RHD over the next decade.

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“…There is an inherited susceptibility to ARF, 17 but the basis for this susceptibility has yet to be clarified. 18 We have never sought genetic markers for ARF/RHD using modern techniques.…”

Section: B Genetics Of This Conditionmentioning

confidence: 99%

Rheumatic Fever and Rheumatic Heart Diseases in Bangladesh: Challenges and Remedies

Rahman

Uddin

et al. 2018

Cardiovasc. j.

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In the 21st century, Rheumatic fever (RF) and Rheumatic heart disease (RHD) are neglected diseases of marginalized communities. Globally, RHD remains the most-common cardiovascular disease in young people aged <25 years. Although RF and RHD have been almost eradicated in areas with established economies, migration from low-income to high-income settings might be responsible for a new burden of RHD in high-income countries. Globally, the prevalence of rheumatic fever (RF) and rheumatic heart disease (RHD) has declined sharply but, in developing countries, RF is still aleading cause of heart disease and, consequently, death in children and young adults. In 2005, it was estimated that over 2.4 million children aged 5-14 years were having RHD globally and 79% of all these cases were from lessdeveloped countries.Cardiovasc. j. 2018; 10(2): 206-211

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Acute rheumatic fever: an important differential diagnosis of septic arthritis

Cited by 12 publications

References 5 publications

Acute rheumatic fever and rheumatic heart disease in Fiji: prospective surveillance, 2005–2007

Acute rheumatic fever and rheumatic heart disease in Fiji: prospective surveillance, 2005–2007

Global research priorities in rheumatic fever and rheumatic heart disease

Rheumatic Fever and Rheumatic Heart Diseases in Bangladesh: Challenges and Remedies

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