Acute Severe Transaminitis as a Unique Presentation of Chronic Cholecystitis

Fatima, Huda; Avasthi, Deepti

doi:10.7759/cureus.16102

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…Routine treatment of cholecystitis primarily focuses on aggressive prevention and treatment of bacterial infections and complications. In chronic cholecystitis, symptomatic antispasmodic, analgesic, and anti-inflammatory treatment, together with daily dietary care, deserve great attention [ 21 ]. In the case of acute cholecystitis, laparoscopic cholecystectomy is the main treatment for cholecystitis.…”

Section: Discussionmentioning

confidence: 99%

Analysis of the Effect of Laparoscopic Cholecystectomy for Acute Cholecystitis after Percutaneous Transhepatic Gallbladder Puncture and Drainage

Yang

Tian

2022

Evidence-Based Complementary and Alternative Medicine

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Objective. To assess the effect of laparoscopic cholecystectomy for acute cholecystitis after percutaneous transhepatic gallbladder drainage (PTGBD). Methods. A total of 70 patients with acute cholecystitis diagnosed and treated in our hospital between April 2020 and November 2021 were recruited and assigned to receive either conventional treatment (conventional group) or PTGBD plus laparoscopic cholecystectomy (experimental group) according to the order of admission (with January 2021 as the cut-off time point), with 35 cases in each group. Outcome measures included treatment outcomes, surgical indices, and postoperative recovery. Results. Patients in the experimental group showed significantly less intraoperative hemorrhage volume and shorter operative time, time-lapse before passing gas, and hospital stay (83.15 ± 31.17, 32.54 ± 12.61, 23.02 ± 4.61, 7.98 ± 3.24) versus those in the conventional group (120.56 ± 30.55, 61.01 ± 15.54, 28.15 ± 5.91, 11.95 ± 4.15) ( P < 0.05 ). The incidence of conversion to open surgery and postoperative drainage in the experimental group was significantly lower (2.86%, 5.71%) than that of the conventional group (25.71%, 45.71%) ( P < 0.05 ). The differences in the postoperative body temperature of the two groups did not come up to statistical standard ( P > 0.05 ). The experimental group had faster body temperature recovery and leukocyte recovery and better leukocyte levels (1.25 ± 0.56, 2.36 ± 0.48, 7.92 ± 1.36) than the conventional group (3.11 ± 1.05, 5.41 ± 0.63, 10.52 ± 2.78) ( P < 0.05 ). There was 1 (2.86%) case of pneumothorax and 1 (2.86%) case of intestinal bleeding in the experimental group, and there were 2 (5.71%) cases of biliary leakage, 3 (8.57%) cases of pneumothorax, 4 (11.43%) cases of intestinal bleeding, 5.71% cases of incisional infection, 1 (2.86%) case of respiratory failure, and 1 (2.86%) case of liver damage in the conventional group. The experimental group showed a significantly lower incidence of complications (5.71%) versus the conventional group (37.14%) ( P < 0.05 ). Conclusion. PTGBD plus laparoscopic cholecystectomy for acute cholecystitis effectively improves surgical safety, promotes patients' postoperative recovery, and reduces the incidence of conversion to open surgery and postoperative complications with a high safety profile. Further trials are, however, required prior to clinical promotion.

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Section: Discussionmentioning

confidence: 99%

Analysis of the Effect of Laparoscopic Cholecystectomy for Acute Cholecystitis after Percutaneous Transhepatic Gallbladder Puncture and Drainage

Yang

Tian

2022

Evidence-Based Complementary and Alternative Medicine

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“…Furthermore, a cat with a duplex gallbladder associated with biliary mucocele and cholelithiasis was reported to also have serum liver enzyme levels within the reference intervals (Woods et al., 2012 ). In humans, abnormal liver enzyme levels are more commonly found in acute cholecystitis than in chronic gallbladder inflammation due to the nature of the inflammatory process (Fatima & Avasthi, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Double cholecystectomy of duplex gallbladder associated with chronic cholecystitis in a cat

Tayayouth,

Kalerum,

Girddee

et al. 2023

Veterinary Medicine & Sci

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A 6‐year‐old female neutered Persian cat presented with hyporexia and gradual weight loss over 6 months. Physical examination revealed cranial abdominal pain. Haematology and serum biochemistry were within normal limits. Abdominal ultrasonography and a computed tomography scan suggested a non‐neoplastic mass compressing the gallbladder. During an exploratory laparotomy, a duplex gallbladder with two separate cystic ducts was diagnosed intraoperatively. The mass identified using the imaging techniques was an abnormal right gallbladder which was distended with immobile mucoid bile and a thickened wall. The left gallbladder and cystic duct were grossly normal. A cholecystectomy of both gallbladders was performed. Histopathology of the right gallbladder identified chronic cholecystitis. The cat made a good recovery from surgery and reported complete resolution of its hyporexia and a return to normal body weight. This is the first report of a successful cholecystectomy of a duplex gallbladder with chronic cholecystitis of a single gallbladder.

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Acute Severe Transaminitis as a Unique Presentation of Chronic Cholecystitis

Cited by 2 publications

References 4 publications

Analysis of the Effect of Laparoscopic Cholecystectomy for Acute Cholecystitis after Percutaneous Transhepatic Gallbladder Puncture and Drainage

Analysis of the Effect of Laparoscopic Cholecystectomy for Acute Cholecystitis after Percutaneous Transhepatic Gallbladder Puncture and Drainage

Double cholecystectomy of duplex gallbladder associated with chronic cholecystitis in a cat

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