“…Most of the studies (n=14, 47%) were from the USA 18,20,29,[53][54][55]57,60,63,64,67,[69][70][71] Three were from Canada, 21,28,51 six from Europe that included two from Norway, 17,68 two from the Netherlands, 58,82 one from Italy 62 and one from Switzerland, 65 four from Asia (Hong Kong, 42,66 Japan, 61 and Taiwan 56 ), two from Australia and New Zealand 30,59 and one from South Africa. 52 The mean age of patients varied between regions, from an overall median age of 27 years in the South African study 52 to 44.9 years for the direct group and 45.9 years for the transfer group in the three Canadian studies.…”