Acute symmetric peripheral gangrene following a long-standing Mycobacterium malmoense infection: A very rare kinship

Maruma, Frans; Carter, Richard; Moosa, F; Makuru, Harriet; Asmal, Taahir

doi:10.1016/j.jdcr.2020.07.051

Cited by 1 publication

(1 citation statement)

References 12 publications

(13 reference statements)

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“…The majority presented with multiple erythematous or violaceous macules, papules, or firm nodules on the palms and soles that had persisted for weeks to months. Primary skin infection with Mycobacterium malmoense has caused leukocytoclastic vasculitis presenting as symmetrical peripheral gangrene in an HIV‐negative 37‐year‐old male 12 . These cases highlight the importance of a high index of suspicion for NTM infection and public health monitoring, as well as the need for better infection control measures to prevent future outbreaks.…”

Section: Clinical Featuresmentioning

confidence: 99%

Dermatology practice updates in mycobacterial disease

Barker,

Alshaikh,

Elston

2023

Int J Dermatology

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Atypical mycobacterial infections are commonly acquired through exposure to water, and tuberculosis remains highly endemic in many parts of the world. In this era of global connection, travel, and immigration, it is more important than ever to maintain a high index of suspicion for infection from cutaneous tuberculosis and atypical mycobacteria. Epidemics related to surgical procedures have been related to inadequate sterilization, as almost 50% of public water supplies harbor mycobacteria. Improved diagnostic techniques for these microbes, including Auramine–Rhodamine staining and rapid detection of mycobacteria and drug susceptibilities through PCR and MALDI‐TOF, have improved detection and treatment outcomes. Given an increasing number of patients on immunosuppressive therapies, clinicians must remain vigilant.

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Section: Clinical Featuresmentioning

confidence: 99%