Acute Tetraplegia Caused by Rat Bite Fever in Snake Keeper and Transmission of <i>Streptobacillus moniliformis</i>

Eisenberg, Tobias; Poignant, Simon; Jouan, Youenn; Fawzy, Ahmad; Nicklas, Werner; Ewers, Christa; Mereghetti, Laurent; Guillon, Antoine

doi:10.3201/eid2304.161987

Cited by 20 publications

(13 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, Eisenberg et al reported acute tetraplegia in a snake keeper in relation to RBF. The patient’s condition was so bad that he was sedated, mechanically ventilated and even admitted to the intensive care unit [12]. Endocarditis is the primary cause of death, accounting for up to 53% of cases of morality [9, 13, 14].…”

Section: Discussionmentioning

confidence: 99%

Rat bite fever caused by Streptobacillus moniliformis infection in a Chinese patient

Zhang

Guo-xin

et al. 2019

BMC Infect Dis

View full text Add to dashboard Cite

Background Rat bite fever (RBF), a severe infectious disease, can result from transmission of the pathogen Streptobacillus moniliformis ( S. moniliformis ) by rat bite. RBF diagnosis can be overlooked. Case presentation We present a case of RBF in a Chinese patient who was infected with S. moniliformis in mainland China. Meta-next generation sequencing (mNGS) was used to identify potential pathogens and detected S. moniliformis genome sequences in the pustular sample in less than 72 h. Then the diagnosis was validated by polymerase chain reaction analysis. Despite having severe RBF with complications, this 54-year-old male patient was successfully cured with penicillin as a result of timely pathogen-based diagnosis. Conclusions Physicians should inquire about recent rat exposure and consider the possibility of RBF when a patient develops unexplained fever and rashes. mNGS is a new diagnostic technology and may identify RBF pathogens even when blood culture results are negative.

show abstract

Section: Discussionmentioning

confidence: 99%

Rat bite fever caused by Streptobacillus moniliformis infection in a Chinese patient

Zhang

Guo-xin

et al. 2019

BMC Infect Dis

View full text Add to dashboard Cite

show abstract

“…PubMed was searched for the following terms: Spirillum minus, Streptobacillus moniliformis, Haverhillia multiformis, rat bite fever, AND osteomyelitis, discitis. Our literature review uncovered associated with S. moniliformis, only 4 cases of osteomyelitis, 1 of possible osteomyelitis, and 4 of discitis, reported globally [6][7][8][9][10][11][12][13][14]. It is difficult to judge in our case whether the findings on MR imaging represent discitis or rather extension of infection from the L2-L3 endplate.…”

Section: Discussionmentioning

confidence: 77%

Rat bite fever with osteomyelitis and discitis: case report and literature review

Adams

Mahapatra

2021

BMC Infect Dis

View full text Add to dashboard Cite

Background Rat bite fever (RBF) is a rare systemic febrile illness transmitted by rats. Streptobacillus moniliformis is a pleomorphic Gram-negative bacillus which is the usual etiologic organism for rat bite fever in the United States. Case presentation Here we present a case of rat bite fever complicated by vertebral osteomyelitis and discitis. The patient revealed an exposure history of being bitten by pet rats. The patient’s symptoms dramatically improved with a six-week course of cephalexin therapy. Conclusions It is important to obtain a thorough zoonotic exposure history and maintain rat bite fever in the differential when considering potential causes of discitis and osteomyelitis.

show abstract

“…Our patient had a fever, rash, and vomiting at presentation. Patients may also present with more serious conditions, such as disturbed consciousness [ 8 ], which might lead to several types of critical complications, including spinal epidural abscess [ 9 ], mitral valve endocarditis and septic arthritis [ 10 ], acute tetraplegia [ 11 ], and vertebral osteomyelitis [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Rat Bite Fever: The First Case Report from Qatar

et al. 2020

View full text Add to dashboard Cite

Patient: Male, 37-year-old Final Diagnosis: Rat bite fever Symptoms: Acute gastroenteritis • fever • headache • loose stools • vomiting Medication: — Clinical Procedure: — Specialty: Critical Care Medicine • Dermatology • Infectious Diseases • Public Health Objective: Rare disease Background: Rat bite fever (RBF) is a rare but fatal zoonotic disease caused by infections with various bacteria, which are transmitted from rats or other rodents. Only a few patients worldwide are diagnosed with RBF annually. RBF can be fatal if left untreated, with a mortality rate of about 10% in patients with severe RBF. Case Report: A case 37-year-old previously healthy man presented to the emergency department with acute gastroenteritis, sepsis and multi-organ failure requiring ventilatory support. He was later diagnosed with RBF due to Streptobacillus moniliformis . He recovered rapidly after administration of intravenous penicillin G and was discharged from the hospital 10 days later. Conclusions: This report describes a patient with RBF and multi-organ involvement requiring ventilatory support. He was successfully treated with intravenous penicillin G. To our knowledge, this is the first report of a patient from Qatar with RBF.

show abstract

Acute Tetraplegia Caused by Rat Bite Fever in Snake Keeper and Transmission of Streptobacillus moniliformis

Cited by 20 publications

References 6 publications

Rat bite fever caused by Streptobacillus moniliformis infection in a Chinese patient

Rat bite fever caused by Streptobacillus moniliformis infection in a Chinese patient

Rat bite fever with osteomyelitis and discitis: case report and literature review

Rat Bite Fever: The First Case Report from Qatar

Contact Info

Product

Resources

About