Patients presenting to the emergency department with hypothermia are rare and
often require prompt diagnosis and management. Myxedema coma, which may cause
severe hypothermia, is a true endocrine emergency requiring early and
appropriate treatment. We report on a 47-year-old woman with a history of
hyperthyroidism who underwent thyroidectomy 5 years previously, with no regular
medication or examinations. She presented to the emergency department with a
1-month history of progressive dyspnea associated with general weakness. She
also showed hypothermia, decreased mental status, and general edema.
Echocardiography revealed increased pericardial effusion without tamponade.
Laboratory examination suggested myxedema coma and hypothyroidism. She received
thyroxine, glucocorticoid supplement, and intensive supportive care, after which
she gradually improved and was discharged. This case suggests that myxedema coma
should be considered in patients with hypothyroidism or a history of
thyroidectomy who present with change in consciousness, hypothermia, or other
symptoms related to critical or slow presentation in multiple organs. Moreover,
long-standing hypothyroidism or precipitating acute events such as sepsis,
cerebrovascular accidents, gastrointestinal bleeding, cold exposure, trauma, and
some medications may also cause myxedema coma. Myxedema coma is associated with
a high mortality, and patients suspected to be suffering from this condition
should be treated without delay.